Asymmetric Ene‐Reduction by F420‐Dependent Oxidoreductases B (FDOR‐B) from Mycobacterium smegmatis
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DOI: 10.1002/cbic.202200797
Abstract: Asymmetric reduction by ene‐reductases has received considerable attention in recent decades. While several enzyme families possess ene‐reductase activity, the Old Yellow Enzyme (OYE) family has received the most scientific and industrial attention. However, there is… read more here.
Keywords: f420; ene; ene reductases; sub group ... See more keywords
Diversification by CofC and Control by CofD Govern Biosynthesis and Evolution of Coenzyme F420 and Its Derivative 3PG-F420
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DOI: 10.1128/mbio.03501-21
Abstract: The microbial cofactor F420 is crucial for processes like methanogenesis, antibiotics biosynthesis, drug resistance, and biocatalysis. Recently, a novel derivative of F420 (3PG-F420) was discovered, enabling the production and use of F420 in heterologous hosts.… read more here.
Keywords: f420; cofd; 3pg f420; coenzyme f420 ... See more keywords
Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria
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DOI: 10.1128/msystems.00389-20
Abstract: Mycobacteria are major environmental microorganisms and cause many significant diseases, including tuberculosis. Mycobacteria make an unusual vitamin-like compound, F420, and use it to both persist during stress and resist antibiotic treatment. Understanding how mycobacteria make… read more here.
Keywords: f420; mycobacteria make; tuberculosis; mycobacteria ... See more keywords