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Treatment of Cytomegalovirus in Human Donor Lungs with a Novel Chemokine-Based Immunotoxin during Ex Vivo Lung Perfusion Prevents Viral Reactivation

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Published in 2021 at "Journal of Heart and Lung Transplantation"

DOI: 10.1016/j.healun.2021.01.938

Abstract: Purpose Post-transplant CMV reactivation from latently-infected lung allografts is extremely prevalent and results in inferior long-term outcomes. CMV latently infected cells ubiquitously express a viral surface protein, US28. We aimed to evaluate the therapeutic effects… read more here.

Keywords: reactivation; lung; immunotoxin; chemokine ... See more keywords