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Two Conserved Phenylalanine Residues in the E1 Fusion Loop of Alphaviruses Are Essential for Viral Infectivity

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Published in 2022 at "Journal of Virology"

DOI: 10.1128/jvi.00064-22

Abstract: Alphaviruses are human pathogens that cause both debilitating acute and chronic musculoskeletal disease and potentially fatal encephalitis. In this study, we determined that two highly conserved phenylalanine residues in the alphavirus E1 glycoprotein are required… read more here.

Keywords: fusion loop; phenylalanine residues; fusion; f87a f95a ... See more keywords