Association of IL-1β, IL-1Ra and FABP1 gene polymorphisms with the metabolic features of polycystic ovary syndrome
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DOI: 10.1007/s00011-017-1045-3
Abstract: BackgroundPolycystic ovary syndrome (PCOS), a highly prevalent endocrinopathy is currently being designated as chronic low grade inflammatory state. IL-1β, IL-1Ra and FABP1 are critical mediators of inflammatory processes and are speculated to play a role… read more here.
Keywords: metabolic features; gene polymorphisms; association; fabp1 gene ... See more keywords
Δ9-Tetrahydrocannabinol induces endocannabinoid accumulation in mouse hepatocytes: antagonism by Fabp1 gene ablation
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DOI: 10.1194/jlr.m082644
Abstract: Phytocannabinoids, such as Δ9-tetrahydrocannabinol (THC), bind and activate cannabinoid (CB) receptors, thereby “piggy-backing” on the same pathway’s endogenous endocannabinoids (ECs). The recent discovery that liver fatty acid binding protein-1 (FABP1) is the major cytosolic “chaperone”… read more here.
Keywords: fabp1 gene; aea; thc; mouse hepatocytes ... See more keywords