Circulating Serum Fatty Acid-Binding Protein 4 Levels Predict the Development of Diabetic Retinopathy in Type 2 Diabetic Patients.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2017.12.022
Abstract: PURPOSE Fatty acid-binding protein 4 (FABP4) has been implicated in the pathology of diabetes and macrovascular diseases. Serum FABP4 levels were determined in type 2 diabetic patients without diabetic retinopathy (DR) at admission in order… read more here.
Keywords: diabetic retinopathy; fabp4; fatty acid; acid binding ... See more keywords
Ectopical expression of FABP4 gene can induce bovine muscle-derived stem cells adipogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.11.067
Abstract: Fatty acid binding protein 4 (FABP4) plays a key role in Fatty acid catabolism in mammals. Findings from our previous studies have indicated that FABP4 neither affect the differentiation of bovine preadipocytes nor does it… read more here.
Keywords: fabp4; muscle derived; derived stem; expression ... See more keywords
Impact of arsenic exposure on clinical biomarkers indicative of cardiovascular disease risk in Mexican women.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2018.11.088
Abstract: An appropriate and precise identification of high-risk individuals to develop cardiovascular diseases (CVD) is of high importance to reduce these kinds of diseases, a major health concern worldwide. Therefore, the aim of this research was… read more here.
Keywords: risk; mexican women; cvd biomarkers; fabp4 ... See more keywords
PPARγ regulates fabp4 expression to increase DHA content in golden pompano (Trachinotus ovatus) hepatocytes
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Nutrition"
DOI: 10.1017/s0007114521000775
Abstract: Abstract N-3 long-chain (≥C20) PUFA (LC-PUFA) are vital fatty acids for fish and humans. As a main source of n-3 LC-PUFA for human consumers, the n-3 LC-PUFA content of farmed fish is important. Previously, we… read more here.
Keywords: trachinotus ovatus; dha content; fabp4; promoter ... See more keywords
Pharmacological inhibition of fatty acid-binding protein 4 (FABP4) protects against renal ischemia-reperfusion injury
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c8ra00122g
Abstract: Fatty acid-binding protein 4 (FABP4) is a key mediator of endoplasmic reticulum (ER) stress and apoptosis in diabetes and atherosclerosis. Studies also confirmed that circulating FABP4 depended on renal function in chronic kidney disease (CKD)… read more here.
Keywords: protein; fabp4; fatty acid; inhibition ... See more keywords
Fatty acid-binding protein 4 (FABP4) inhibition promotes locomotor and autonomic recovery in rats following spinal cord injury.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurotrauma"
DOI: 10.1089/neu.2021.0346
Abstract: The inflammatory response associated with traumatic spinal cord injury (SCI) contributes to locomotor and sensory impairments. Pro-inflammatory (M1) macrophages/microglia (MφMG) are the major cellular players in this response as they promote chronic inflammation resulting in… read more here.
Keywords: cord injury; fabp4; spinal cord; injury ... See more keywords
Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin’s glucose-lowering effects
Sign Up to like & getrecommendations! Published in 2017 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aad4000
Abstract: Inhibition of FABP4 rescues defective apelin signaling, decreases fatty acid accumulation, and promotes insulin sensitivity. An apelin a day keeps the doctor away Apelin is an atheroprotective protein, which promotes insulin sensitivity and metabolic health,… read more here.
Keywords: aplnr; fabp4; apelin; fatty acid ... See more keywords
Abstract 14880: Single-cell Transcriptomes Identify Unique Endothelial Subpopulation (FABP4 + TMEM100 - ) With Lipid Metabolism Dysfunction in Pulmonary Arterial Hypertension
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.14880
Abstract: Introduction: Pulmonary arterial hypertension (PAH) is a disaster disease characterized by obliterative vascular remodeling and persistent increase of vascular resistance, leading to right heart failure and premature death. Understanding the cellular and molecular mechanisms will… read more here.
Keywords: pah; mice; egln1 tie2cre; fabp4 ... See more keywords
Significance of urinary fatty acid-binding protein 4 level as a possible biomarker for the identification of minimal change disease in patents with nephrotic-range proteinuria
Sign Up to like & getrecommendations! Published in 2020 at "BMC Nephrology"
DOI: 10.1186/s12882-020-02122-y
Abstract: Background Fatty acid-binding protein 4 (FABP4), but not FABP1 (liver-type FABP), is ectopically induced in injured glomerular endothelial cells, and urinary FABP4 (U-FABP4) level is associated with proteinuria and renal dysfunction in a general population.… read more here.
Keywords: fabp4; change; fatty acid; proteinuria ... See more keywords
The adipokine fatty-acid binding protein 4 and cardiac remodeling
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Diabetology"
DOI: 10.1186/s12933-020-01080-x
Abstract: Background Previous publications about the association between fatty-acid binding protein 4 (FABP4) and cardiac remodeling have reported different, both beneficial and harmful, associations. Aim of the present investigation was to evaluate the association of FABP4… read more here.
Keywords: fabp4 levels; fabp4; fatty acid; association ... See more keywords
Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Lipid Research"
DOI: 10.1194/jlr.m074542
Abstract: Previous studies have shown that reduced levels of the adipocyte fatty acid binding protein (FABP)4 (AFABP/aP2), result in metabolic improvement including potentiated insulin sensitivity and attenuated atherosclerosis. Mechanistically, pharmacologic or genetic inhibition of FABP4 in… read more here.
Keywords: protein; fabp4; fatty acid; blt1r expression ... See more keywords