Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202501046
Abstract: Facet joint osteoarthritis (FJOA) is a prevalent degenerative condition in the aging population; however, the underlying pathophysiological mechanisms remain poorly understood and current therapeutic strategies remain limited to palliative pain management. In this study, novel… read more here.
Keywords: facet joint; non canonical; joint osteoarthritis; talin2 ... See more keywords
Feasibility study for evaluating early lumbar facet joint degeneration using axial T1ρ, T2, and T2* mapping in cartilage
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25596
Abstract: To assess the feasibility of axial T2, T2* , and T1ρ mapping of lumbar facet joint (LFJ) cartilage for evaluation of early degeneration. read more here.
Keywords: lumbar facet; feasibility; axial mapping; facet joint ... See more keywords
Increased vertebral body area, disc and facet joint degeneration throughout the lumbar spine in patients with lumbosacral transitional vertebrae
Sign Up to like & getrecommendations! Published in 2022 at "European Radiology"
DOI: 10.1007/s00330-022-08736-0
Abstract: Lumbosacral transitional vertebrae (LSTV), developmental spinal canal stenosis, lumbar disc and facet joint degeneration are all common lumbar spine conditions. This study explores the relationship between these entities. Five hundred and five patients (254 females,… read more here.
Keywords: vertebral body; facet joint; joint degeneration; degeneration ... See more keywords
Lumbar epidural and cervical facet joint injection techniques
Sign Up to like & getrecommendations! Published in 2018 at "European Spine Journal"
DOI: 10.1007/s00586-018-5661-6
Abstract: Image guided anaesthetic blocks play an increasing role in the diagnostics as well as the treatment of spinal disorders. In the workup of many painful conditions, especially degenerative disorders, they are able to add a… read more here.
Keywords: joint injection; lumbar epidural; facet joint; injection ... See more keywords
Modifications in lumbar facet joint are associated with spondylolisthesis in the degenerative spine diseases: a comparative analysis
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-020-04657-3
Abstract: Background Magnetic resonance imaging (MRI) is important in the assessment of degenerative spine disease. However, its role is limited in the identification of spinal instability; therefore, weight-bearing and dynamic studies like X-rays are required. The… read more here.
Keywords: facet fluid; spondylolisthesis; fluid; degenerative spine ... See more keywords
Association of facet tropism and orientation with lumbar disc herniation in young patients
Sign Up to like & getrecommendations! Published in 2018 at "Neurological Sciences"
DOI: 10.1007/s10072-018-3270-0
Abstract: Facet tropism and orientation are thought to be associated with lumbar disc herniation (LDH), but the relationship is not well established. Moreover, the effect of facet joint on LDH has not been outlined in young… read more here.
Keywords: young patients; tropism orientation; facet joint; tropism ... See more keywords
MiR-337-3p confers protective effect on facet joint osteoarthritis by targeting SKP2 to inhibit DUSP1 ubiquitination and inactivate MAPK pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology and toxicology"
DOI: 10.1007/s10565-021-09665-2
Abstract: OBJECTIVE To probe the performance of miR-337-3p on the facet joint osteoarthritis (FJOA) and its underlying mechanism. METHODS qRT-PCR and Western blot were utilized to analyze the levels of miR-337-3p and DUSP1 in the synovial… read more here.
Keywords: mir 337; dusp1; facet joint; joint osteoarthritis ... See more keywords
Three-dimensional digital measurement of the facet joint in normal and lumbar intervertebral disc herniation aged 13-18 years.
Sign Up to like & getrecommendations! Published in 2021 at "Asian journal of surgery"
DOI: 10.1016/j.asjsur.2021.05.028
Abstract: BACKGROUND Lumbar facet joint is an important element of spinal "three-joint complex". Whether there is a relationship between strange structure of facet joint and adolescent lumbar disc herniation (ALDH) is nonetheless controversial, and the current… read more here.
Keywords: facet; disc herniation; facet joint; lumbar ... See more keywords
Facet joint injection versus epidural steroid injection for lumbar spinal stenosis: intra-individual study.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical radiology"
DOI: 10.1016/j.crad.2016.08.006
Abstract: AIM To evaluate the efficacy of facet joint injection (FJI) for patients with lumbar central canal stenosis (LCS) in comparison with epidural steroid injection (ESI) in the same individuals. MATERIAL AND METHODS Two hundred and… read more here.
Keywords: joint injection; steroid injection; study; facet joint ... See more keywords
Segmental variations in facet joint translations during in vivo lumbar extension.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biomechanics"
DOI: 10.1016/j.jbiomech.2017.09.026
Abstract: The lumbar facet joint (FJ) is often associated with pathogenesis in the spine, but quantification of normal FJ motion remains limited to in vitro studies or static imaging of non-functional poses. The purpose of this… read more here.
Keywords: segmental variations; kinematics; translation; facet joint ... See more keywords
Biomechanical Analysis of Bilateral Facet Joint Stabilization Using Bioderived Tendon for Posterior Cervical Spine Motion Reservation in Goats.
Sign Up to like & getrecommendations! Published in 2017 at "World neurosurgery"
DOI: 10.1016/j.wneu.2017.07.163
Abstract: OBJECTIVES To investigate the biomechanical properties of a novel stabilization method for posterior cervical motion preservation using bioderived freeze-dried tendon. METHODS Experiments were conducted both in vitro and in vivo. For the in vitro group, 15 fresh-frozen goat… read more here.
Keywords: motion; stabilization; bioderived tendon; bilateral facet ... See more keywords