Facile target validation in an animal model with intracellularly expressed monobodies
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DOI: 10.1038/s41589-018-0099-z
Abstract: Rapidly determining the biological effect of perturbing a site within a potential drug target could guide drug discovery efforts, but it remains challenging. Here, we describe a facile target validation approach that exploits monobodies, small… read more here.
Keywords: monobody; validation; target; facile target ... See more keywords