Aß Facilitates LTD at Schaffer Collateral Synapses Preferentially in the Left Hippocampus.
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DOI: 10.1016/j.celrep.2018.01.085
Abstract: Promotion of long-term depression (LTD) mechanisms by synaptotoxic soluble oligomers of amyloid-β (Aß) has been proposed to underlie synaptic dysfunction in Alzheimer's disease (AD). Previously, LTD was induced by relatively non-specific electrical stimulation. Exploiting optogenetics,… read more here.
Keywords: schaffer collateral; hippocampus; left hippocampus; ltd schaffer ... See more keywords