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   Articles with "factor" as a keyword



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Factors Associated With Visual Acuity and Central Subfield Thickness Changes When Treating Diabetic Macular Edema With Anti–Vascular Endothelial Growth Factor Therapy: An Exploratory Analysis of the Protocol T Randomized Clinical Trial

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recommendations! Published in 2019 at "JAMA Ophthalmology"

DOI: 10.1001/jamaophthalmol.2018.6786

Abstract: Importance Identifying the factors that are associated with the magnitude of treatment benefits from anti–vascular endothelial growth factor (anti-VEGF) therapy for diabetic macular edema (DME) may help refine treatment expectations. Objective To identify the baseline… read more here.

Keywords: anti vegf; improvement; subfield thickness; factors associated ... See more keywords
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Evaluating the Occurrence of Rare Variants in the Complement Factor H Gene in Patients With Early-Onset Drusen Maculopathy.

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recommendations! Published in 2021 at "JAMA ophthalmology"

DOI: 10.1001/jamaophthalmol.2021.4102

Abstract: Importance Early-onset drusen maculopathy (EODM) is a severe disease and can lead to advanced macular degeneration early in life; however, genetic and phenotypic characteristics of individuals with EODM are not well studied. Objective To identify… read more here.

Keywords: early onset; age; factor; gene ... See more keywords
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Upstream stimulating factor 1 suppresses autophagy and hepatic lipid droplet catabolism by activating mTOR

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recommendations! Published in 2018 at "Febs Letters"

DOI: 10.1002/1873-3468.13203

Abstract: Previous studies indicate that the transcription factor upstream stimulating factor 1 (USF1) is involved in the regulation of lipid and glucose metabolism. However, the role of USF1 in lipid‐induced autophagy remains unknown. Interestingly, we found… read more here.

Keywords: suppresses autophagy; stimulating factor; upstream stimulating; mtor ... See more keywords
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Site‐specific functional roles of the Factor X activation peptide in the intrinsic tenase‐mediated Factor X activation

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14321

Abstract: The conversion of zymogen Factor X (FX) to an active protease involves the removal of a 52‐residue long activation peptide (AP). Through site‐directed mutagenesis, we investigate the role of the AP and demonstrate that the… read more here.

Keywords: intrinsic tenase; factor activation; factor; site ... See more keywords
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Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia-inducible factor-1α in colorectal cancer.

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recommendations! Published in 2021 at "Molecular oncology"

DOI: 10.1002/1878-0261.13044

Abstract: Distant metastasis is a major cause of death in patients with colorectal cancer (CRC), but the management of advanced and metastatic CRC still remains problematic due to the distinct molecular alterations during tumor progression. Tumor… read more here.

Keywords: tumor; factor; crc; scg2 ... See more keywords
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MSK1 regulates transcriptional induction of Arc/Arg3.1 in response to neurotrophins

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recommendations! Published in 2017 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12232

Abstract: The immediate early gene activity‐regulated cytoskeletal protein (Arc)/Arg3.1 and the neurotrophin brain‐derived neurotrophic factor (BDNF) play important roles in synaptic plasticity and learning and memory in the mammalian brain. However, the mechanisms by which BDNF… read more here.

Keywords: msk1; arc arg3; factor; response ... See more keywords
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Tacorin, an extract from Ananas comosus stem, stimulates wound healing by modulating the expression of tumor necrosis factor α, transforming growth factor β and matrix metalloproteinase 2

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recommendations! Published in 2017 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12241

Abstract: Wound healing is a complex biological process that involves integration of hemostasis, inflammation, proliferation and tissue remodeling. An extract of pineapple (Ananas comosus) stem demonstrates several therapeutics properties, including acceleration of wound healing. Tacorin is… read more here.

Keywords: ananas comosus; wound healing; expression; tacorin ... See more keywords
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Induction of ubiquitin C (UBC) gene transcription is mediated by HSF1: role of proteotoxic and oxidative stress

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recommendations! Published in 2018 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12484

Abstract: The polyubiquitin gene ubiquitin C (UBC) is considered a stress protective gene and is upregulated under various stressful conditions, which is probably a consequence of an increased demand for ubiquitin in order to remove toxic… read more here.

Keywords: transcription; ubc gene; factor; stress ... See more keywords

Maturation of coagulation factor IX during Xase formation as deduced using factor VIII‐derived peptides

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recommendations! Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12653

Abstract: Blood coagulation involves extrinsic and intrinsic pathways, which merge at the activation step of blood coagulation factor X to factor Xa. This step is catalysed by the extrinsic or intrinsic Xase, which consists of a… read more here.

Keywords: coagulation; xase; fviiia; coagulation factor ... See more keywords
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Unusual Spectrally Reproducible and High Q‐Factor Random Lasing in Polycrystalline Tin Perovskite Films

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recommendations! Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202208293

Abstract: An unusual spectrally reproducible near‐IR random lasing (RL) with no fluctuation of lasing peak wavelength is disclosed in polycrystalline films of formamidinium tin triiodide perovskite, which have been chemically stabilized against Sn2+ to Sn4+ oxidation.… read more here.

Keywords: unusual spectrally; random lasing; factor; tin ... See more keywords
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Fibroblast Growth Factor 2‐Mediated Regulation of Neuronal Exosome Release Depends on VAMP3/Cellubrevin in Hippocampal Neurons

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recommendations! Published in 2020 at "Advanced Science"

DOI: 10.1002/advs.201902372

Abstract: Abstract Extracellular vesicles (EVs) are endogenous membrane‐derived vesicles that shuttle bioactive molecules between glia and neurons, thereby promoting neuronal survival and plasticity in the central nervous system (CNS) and contributing to neurodegenerative conditions. Although EVs… read more here.

Keywords: vamp3 cellubrevin; hippocampal neurons; fibroblast growth; growth factor ... See more keywords