The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington’s disease
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DOI: 10.1007/s00401-017-1770-2
Abstract: Activating transcription factor-5 (ATF5) is a stress-response transcription factor induced upon different cell stressors like fasting, amino-acid limitation, cadmium or arsenite. ATF5 is also induced, and promotes transcription of anti-apoptotic target genes like MCL1, during… read more here.
Keywords: atf5; transcription; polyglutamine; transcription factor ... See more keywords