Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
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DOI: 10.1016/j.celrep.2017.08.081
Abstract: The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Disruption of its interaction with transcriptional repressors interferes with the oncogenic effects of BCL6. We… read more here.
Keywords: transcription factor; degradation; bcl6; factor bcl6 ... See more keywords