Articles with "factor beta" as a keyword



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Ultrastructural and Molecular Characterization of Platelet-derived growth factor Beta-Positive Leptomeningeal Cells in the Adult Rat Brain

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Published in 2019 at "Molecular Neurobiology"

DOI: 10.1007/s12035-019-01793-5

Abstract: The leptomeninges, referring to the arachnoid and pia mater and their projections into the perivascular compartments in the central nervous system, actively participate in diverse biological processes including fluid homeostasis, immune cell infiltrations, and neurogenesis,… read more here.

Keywords: pdgfr cells; factor beta; growth factor; pdgfr ... See more keywords
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Ligand-based computational modelling of platelet-derived growth factor beta receptor leading to new angiogenesis inhibitory leads

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Published in 2017 at "Computational biology and chemistry"

DOI: 10.1016/j.compbiolchem.2017.10.003

Abstract: Platelet derived growth factor beta receptor (PDGFR- β) plays an important role in angiogenesis. PDGFR-β expression is correlated with increased vascularity and maturation of blood vessels in cancer. Pharmacophore modeling and quantitative structure-activity relationship (QSAR)… read more here.

Keywords: angiogenesis; factor beta; beta receptor; growth factor ... See more keywords
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Altered transforming growth factor beta/SMAD3 signalling in patients with hippocampal sclerosis

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Published in 2018 at "Epilepsy Research"

DOI: 10.1016/j.eplepsyres.2018.08.004

Abstract: Transforming growth factor beta (TGFβ) signalling cascade has been implicated in enhancing neuronal excitability and excitatory synaptogenesis following blood brain barrier (BBB) damage and inflammation. We aimed to study if TGFβ signalling expression is altered… read more here.

Keywords: growth factor; factor beta; transforming growth;
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Transforming growth factor-beta 1 polymorphisms and anti-tuberculosis drug-induced liver injury. Polymorphisms in TGFβ1 and its relationship with anti-tuberculosis drug-induced liver injury.

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Published in 2019 at "Therapie"

DOI: 10.1016/j.therap.2018.07.003

Abstract: AIM There is evidence to suggest that transforming growth factor-beta 1 takes part in a series of physiological and pathological processes in the human body, including wound healing, tissue fibrosis and embryonic development. We hypothesized… read more here.

Keywords: growth factor; factor beta; anti tuberculosis; transforming growth ... See more keywords
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Circulating levels of transforming growth factor beta-1, 2 and 3 in HIV associated preeclamptic pregnancies

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Published in 2022 at "Journal of Obstetrics and Gynaecology"

DOI: 10.1080/01443615.2022.2110458

Abstract: Abstract The active role of transforming growth factor-beta in implantation, embryonic development and decidualization has driven our interest to evaluate circulating TGF-β(1–3) in the synergy of HIV associated pregnancy. Serum TGF-β(1–3) was quantified in normotensive… read more here.

Keywords: transforming growth; hiv; hiv associated; factor beta ... See more keywords
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Identifying and categorizing compounds that reduce corneal transforming growth factor beta induced protein levels: a scoping review

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Published in 2022 at "Expert Review of Clinical Pharmacology"

DOI: 10.1080/17512433.2022.2142560

Abstract: ABSTRACT Introduction Transforming growth factor beta induced (TGFBI) gene mutations have been reported as the cause of a group of genetically inherited, visually debilitating, corneal dystrophies (CD). A scoping literature review to identify and categorize… read more here.

Keywords: beta induced; factor beta; transforming growth; growth factor ... See more keywords
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High expression of small nucleolar RNA host gene 3 predicts poor prognosis and promotes bone metastasis in prostate cancer by activating transforming growth factor-beta signaling

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2020393

Abstract: ABSTRACT Bone metastasis is closely related to tumor death in prostate cancer (PC). Long noncoding RNA small nucleolar RNA host gene 3 (SNHG3) has been implicated in the initiation and progression of multiple human cancers.… read more here.

Keywords: metastasis; transforming growth; bone metastasis; factor beta ... See more keywords
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Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

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Published in 2020 at "Mediators of Inflammation"

DOI: 10.1155/2020/3185015

Abstract: Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-β pathway is known to play a role in immune response, angiogenesis, inflammation, hematopoiesis, vascular inflammation, and cell proliferation. Polymorphisms in… read more here.

Keywords: transforming growth; factor beta; beta receptor; growth factor ... See more keywords
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Abstract 897: Association between transforming growth factor beta 1 and progression-free survival in breast cancer

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Published in 2021 at "Epidemiology"

DOI: 10.1158/1538-7445.am2021-897

Abstract: Transforming growth factor-beta 1 (TGF-β1) has a dual role in cancer progression, with inhibitory functions in early tumor stages and tumor promotion in advanced stages. However, most prior studies have studied survival in either all… read more here.

Keywords: progression; factor beta; transforming growth; cancer ... See more keywords
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LTBP4 (Latent Transforming Growth Factor Beta Binding Protein 4) Protects Against Renal Fibrosis via Mitochondrial and Vascular Impacts.

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Published in 2023 at "Circulation research"

DOI: 10.1161/circresaha.123.322494

Abstract: BACKGROUND As a part of natural disease progression, acute kidney injury (AKI) can develop into chronic kidney disease via renal fibrosis and inflammation. LTBP4 (latent transforming growth factor beta binding protein 4) regulates transforming growth… read more here.

Keywords: transforming growth; renal fibrosis; factor beta; ltbp4 ... See more keywords
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Transforming growth factor beta 1 polymorphisms and haplotypes associated with breast cancer susceptibility: A case-control study in Tunisian women

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Published in 2019 at "Tumor Biology"

DOI: 10.1177/1010428319869096

Abstract: Variable association of transforming growth factor beta 1 (TGFβ1) in breast cancer (BC) pathogenesis was documented, and the contribution of specific TGFB1 polymorphisms to the progression of BC and associated features remains poorly understood. We… read more here.

Keywords: transforming growth; susceptibility; factor beta; growth factor ... See more keywords