Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development.
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DOI: 10.1182/bloodadvances.2022009438
Abstract: Acute myeloid leukemia (AML) is an aggressive blood cancer that stems from the rapid expansion of immature leukemic blasts in the bone marrow. Mutations in epigenetic factors represent the largest category of genetic drivers of… read more here.
Keywords: aml; repression; chromatin assembly; factor chaf1b ... See more keywords