The GATA Transcription Factor Gaf1 Represses tRNAs, Inhibits Growth, and Extends Chronological Lifespan Downstream of Fission Yeast TORC1
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DOI: 10.1016/j.celrep.2020.02.058
Abstract: Summary Target of Rapamycin Complex 1 (TORC1) signaling promotes growth and aging. Inhibition of TORC1 leads to reduced protein translation, which promotes longevity. TORC1-dependent post-transcriptional regulation of protein translation has been well studied, while analogous… read more here.
Keywords: torc1; growth; fission yeast; factor gaf1 ... See more keywords