The pioneer factor hypothesis is not necessary to explain ectopic liver gene activation.
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DOI: 10.7554/elife.73358
Abstract: The Pioneer Factor Hypothesis (PFH) states that pioneer factors (PFs) are a subclass of transcription factors (TFs) that bind to and open inaccessible sites and then recruit non-pioneer factors (nonPFs) that activate batteries of silent… read more here.
Keywords: gene activation; factor hypothesis; pioneer factor; pioneer ... See more keywords