Comparison of Phenotypic Activated Protein C Resistance Testing With a Genetic Assay for Factor V Leiden
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqy142
Abstract: Objectives: To compare the accuracy and reliability of phenotypic activated protein C resistance (aPC‐R) assays with a genotypic assay for the factor V Leiden F5 p.R506Q (FVL) mutation. Methods: Data were obtained from an electronic… read more here.
Keywords: phenotypic activated; protein resistance; phenotypic; assay factor ... See more keywords
Comparison of Activated Protein C Resistance With Factor V Leiden Testing by Molecular Assay
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqz112.009
Abstract: Factor V Leiden (FVL) is a variant form of coagulation factor V that is the most common inherited risk factor for venous thromboembolism in people of European ancestry. FVL is associated with the missense mutation,… read more here.
Keywords: apcr fvlm; activated protein; factor leiden; factor ... See more keywords
Management of concomitant factor VII deficiency and Factor V Leiden mutation
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.12572
Abstract: Sir, Factor (F) VII is essential for the initiation of coagulation, binding to tissue factor (TF) that is exposed to blood following tissue damage to form the activated FVIIa-TF complex that then activates FIX and… read more here.
Keywords: factor vii; management concomitant; factor leiden; factor ... See more keywords
Myocardial infarction masquerading as myocarditis in a patient with factor V Leiden: unmasked with MR
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-220652
Abstract: We present a case of a 21-year-old man presenting with sharp left-sided chest pain. A CT pulmonary angiogram was negative, ECG was unremarkable and a mild troponin rise was observed. Myocarditis was suspected as the… read more here.
Keywords: factor leiden; myocardial infarction; infarction masquerading; myocarditis ... See more keywords
Henle fiber layer hemorrhage as the first manifestation of factor V Leiden homozygous mutation.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of ophthalmology"
DOI: 10.1177/11206721231154294
Abstract: PURPOSE To report a case of a Henle fiber layer hemorrhage as the initial manifestation of Factor V Leiden disease. METHODS Case report and literature review. RESULTS A healthy 19-year-old patient presented with a spontaneous… read more here.
Keywords: hemorrhage; factor leiden; manifestation factor; henle fiber ... See more keywords
Thrombus stability explains the factor V Leiden paradox: a mouse model.
Sign Up to like & getrecommendations! Published in 2019 at "Blood advances"
DOI: 10.1182/bloodadvances.2019031112
Abstract: Humans carrying the factor V Leiden (FVL) variant have a fivefold increased risk for venous thrombosis. However, incidence of deep vein thrombosis (DVT) is proportionally greater than that of pulmonary embolism (PE) in these individuals.… read more here.
Keywords: f5l mice; paradox; dvt; factor leiden ... See more keywords
Xanthine calculi in a patient with Lesch-Nyhan syndrome and factor V Leiden treated with allopurinol: case report
Sign Up to like & getrecommendations! Published in 2018 at "BMC Pediatrics"
DOI: 10.1186/s12887-018-1197-5
Abstract: BackgroundLesch-Nyhan syndrome is a rare inborn error of purine metabolism marked by a complete deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT). Inherited as an X-linked recessive genetic disorder that primarily affects males, patients with Lesch-Nyhan… read more here.
Keywords: nyhan syndrome; lesch nyhan; case; treated allopurinol ... See more keywords
Risk of venous thromboembolism in association with factor V leiden in cancer patients – The EDITH case-control study
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0194973
Abstract: Background Cancer and factor V Leiden mutation are both risk factors for venous thromboembolism (VTE). Cancer critically increases the thrombotic risk whereas Factor V Leiden is the most common pro-thrombotic mutation. The impact of the… read more here.
Keywords: cancer; leiden mutation; risk; factor leiden ... See more keywords
Below-Knee Amputation Resulting from an Arterial Thrombosis from Tourniquet Use in a Patient with Undiagnosed Factor V Leiden: A Case Report.
Sign Up to like & getrecommendations! Published in 2020 at "JBJS case connector"
DOI: 10.2106/jbjs.cc.19.00457
Abstract: CASE A 38-year-old woman presented with previously undiagnosed factor V Leiden (FVL), who suffered a complete superficial femoral arterial thrombosis after tourniquet use during the surgical repair of one of her bilateral tibial plafond fractures.… read more here.
Keywords: factor leiden; undiagnosed factor; tourniquet use; case ... See more keywords
The relationship between the levels and function of endothelial progenitor cells and factor V Leiden and protein C deficiency in patients with primary Budd-Chiari syndrome.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201805_14971
Abstract: OBJECTIVE Budd-Chiari syndrome (BCS) is a life-threatening hepatic disease characterized by hepatic venous obstruction at the level of hepatic vein, hepatic venules, or inferior vena cava. No evidence reported the relationship between the endothelial progenitor… read more here.
Keywords: protein; protein deficiency; factor leiden; leiden protein ... See more keywords
Ophthalmic Vein Thrombosis Associated with Factor V Leiden and MTHFR Mutations
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13061052
Abstract: Superior ophthalmic vein thrombosis (SOVT) is a rare clinical entity that may be associated with hypercoagulability status. We present a case of a 77-year-old woman who presented to the emergency department complaining of eye ptosis,… read more here.
Keywords: ophthalmic vein; factor leiden; vein thrombosis; eye ... See more keywords