Distinct transcription factor networks control neutrophil-driven inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Nature immunology"
DOI: 10.1038/s41590-021-00968-4
Abstract: Neutrophils display distinct gene expression patters depending on their developmental stage, activation state and tissue microenvironment. To determine the transcription factor networks that shape these responses in a mouse model, we integrated transcriptional and chromatin… read more here.
Keywords: transcription factor; inflammation; control neutrophil; factor networks ... See more keywords
Deregulation of Transcription Factor Networks Driving Cell Plasticity and Metastasis in Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.753456
Abstract: Pancreatic cancer is a very aggressive disease with 5-year survival rates of less than 10%. The constantly increasing incidence and stagnant patient outcomes despite changes in treatment regimens emphasize the requirement of a better understanding… read more here.
Keywords: cancer; transcription factor; pancreatic cancer; factor networks ... See more keywords
LSD1 inhibition modulates transcription factor networks in myeloid malignancies
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1149754
Abstract: Acute Myeloid Leukemia (AML) is a type of cancer of the blood system that is characterized by an accumulation of immature hematopoietic cells in the bone marrow and blood. Its pathogenesis is characterized by an… read more here.
Keywords: transcription; transcription factor; transcription factors; factor networks ... See more keywords