Three-Factor Versus Four-Factor Prothrombin Complex Concentrate for the Emergent Management of Warfarin-Associated Intracranial Hemorrhage
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DOI: 10.1007/s12028-017-0374-y
Abstract: BackgroundFour-factor prothrombin complex concentrates (PCC) produce a more rapid and complete INR correction compared with 3-factor PCC in patients receiving warfarin. It is unknown if this improves clinical outcomes in the setting of intracranial hemorrhage… read more here.
Keywords: mortality; factor pcc; factor; warfarin associated ... See more keywords
Comparing Factor Concentrates for Post-Bypass Coagulopathy: Is There One Best Option?
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DOI: 10.1053/j.jvca.2017.09.009
Abstract: TRADITIONAL MANAGEMENT of post-bypass coagulopathy often relies on the transfusion of fresh frozen plasma and platelets in order to achieve acceptable hemostasis. However, this can often be detrimental to both cardiac function and hemodynamic stability… read more here.
Keywords: bypass coagulopathy; post bypass; factor concentrates; factor pcc ... See more keywords
955: IMPACT OF APPROPRIATE USE OF 4-FACTOR PCC ON BLOOD PRODUCT ADMINISTRATION
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DOI: 10.1097/01.ccm.0000528962.32436.21
Abstract: Critical Care Medicine • Volume 46 • Number 1 (Supplement) www.ccmjournal.org Learning Objectives: Four factor PCC is recommended for intracranial hemorrhage (ICH) associated with vitamin k antagonist. Limited data exists supporting off-labeled indications and outcomes.… read more here.
Keywords: medicine; administration; use; pcc ... See more keywords
709: SAFETY OF 4-FACTOR PCC FOR REVERSAL OF FXA INHIBITORS VERSUS WARFARIN IN NEUROCRITICAL CARE PATIENTS
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DOI: 10.1097/01.ccm.0000551460.73571.35
Abstract: Learning Objectives: Posterior reversible encephalopathy syndrome (PRES) is a state of hyperperfusion and endothelial dysfunction that can present with headache, seizure, encephalopathy, visual impairment, severe hypertension, and cerebral edema on magnetic resonance imaging (MRI). We… read more here.
Keywords: pazopanib; pcc reversal; safety factor; 709 safety ... See more keywords
Reversal Agents for Oral Antiplatelet and Anticoagulant Treatment During Bleeding Events: Current Strategies.
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DOI: 10.2174/1381612822666161205110843
Abstract: There is an increasing prevalence of cardiovascular diseases that warrant antithrombotic therapy. Antithrombotic therapy includes antiplatelet agents and anticoagulation therapy with vitamin K antagonists (VKAs) or non-Vitamin K oral anticoagulants (NOACs). Antithrombotic therapy is associated… read more here.
Keywords: therapy; recommend discontinuation; antithrombotic therapy; factor pcc ... See more keywords