Articles with "factor related" as a keyword



Circulating complement factor H-related protein 5 levels contribute to development and progression of IgA nephropathy.

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Published in 2018 at "Kidney international"

DOI: 10.1016/j.kint.2018.02.023

Abstract: IgA nephropathy (IgAN) is a disease associated with activation of the complement system. But the factors influencing complement activation in IgAN are not fully understood. Complement factor H (FH) is an essential negative regulator of… read more here.

Keywords: iga nephropathy; complement factor; progression; factor related ... See more keywords

Identification of Neurotrophic Factor Related Biomarkers and Mechanistic Insights into Neuropathic Pain via Integrated Bioinformatics Analysis

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Published in 2025 at "ACS Omega"

DOI: 10.1021/acsomega.5c07765

Abstract: Neurotrophic factors are closely associated with the development of neuropathic pain (NPP), yet their underlying mechanisms remain unclear. This study aims to identify key biomarkers and explore their potential mechanisms using integrated bioinformatics approaches. The… read more here.

Keywords: neurotrophic factor; factor related; analysis; cell ... See more keywords
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Pharmacodynamic effects in blood and tumor tissue of eftozanermin alfa, a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist.

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Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.15_suppl.e15668

Abstract: e15668Background: Eftozanermin alfa (eftoza; formerly known as ABBV-621), a 2nd-generation tumor necrosis factor-related apoptosis-inducing ligand receptor agonist, is being evaluated in previously... read more here.

Keywords: factor related; related apoptosis; eftozanermin alfa; tumor necrosis ... See more keywords

A Family Affair: Addressing the Challenges of Factor H and the Related Proteins

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.660194

Abstract: Inflammation is a common denominator of diseases. The complement system, an intrinsic part of the innate immune system, is a key driver of inflammation in numerous disorders. Recently, a family of proteins has been suggested… read more here.

Keywords: related proteins; factor related; family; proteins family ... See more keywords

Role of factor H-related protein 3 in Pseudomonas aeruginosa bloodstream infections

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Published in 2024 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2024.1449003

Abstract: Pseudomonas aeruginosa is a leading cause of nosocomial bloodstream infections. The outcome of these infections depends on the virulence of the microorganism as well as host-related conditions and factors. The complement system plays a crucial… read more here.

Keywords: factor related; role; pseudomonas aeruginosa; factor ... See more keywords

C1q/Tumor Necrosis Factor-Related Protein 9: Basics and Therapeutic Potentials

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Published in 2022 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2022.816218

Abstract: C1q/tumor necrosis factor-related protein 9 (CTRP9) is a newly discovered adipokine that is the closest paralog of adiponectin. Proteolytic cleavage of CTRP9 leads to the release of the globular domain (gCTRP9), which serves as the… read more here.

Keywords: c1q tumor; necrosis factor; related protein; tumor necrosis ... See more keywords

The association between complement C1q tumour necrosis factor-related protein-1 (CTRP-1) level and metabolic syndrome.

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Published in 2023 at "Endokrynologia Polska"

DOI: 10.5603/ep.a2023.0032

Abstract: INTRODUCTION Complement C1q tumour necrosis factor-related protein (CTRP-1) is a member of the C1q protein superfamily that plays a role in metabolism. This retrospective study aimed to investigate associations between CTRP-1 and metabolic syndrome (MetS).… read more here.

Keywords: necrosis factor; related protein; c1q tumour; tumour necrosis ... See more keywords