Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14731
Abstract: Rifampicin, which inhibits bacterial RNA polymerase, provides one of the most effective treatments for tuberculosis. Inhibition of the transcription termination factor Rho is used to treat some bacterial infections, but its importance varies across bacteria.… read more here.
Keywords: transcription; transcription termination; tuberculosis; termination factor ... See more keywords
Termination factor Rho mediates transcriptional reprogramming of Bacillus subtilis stationary phase
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010618
Abstract: Reprogramming of gene expression during transition from exponential growth to stationary phase is crucial for bacterial survival. In the model Gram-positive bacterium Bacillus subtilis, this process is mainly governed by the activity of the global… read more here.
Keywords: termination factor; stationary phase; transcription; factor rho ... See more keywords