Soluble cluster of differentiation 74 regulates lung inflammation through the nuclear factor-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Immunobiology"
DOI: 10.1016/j.imbio.2020.152007
Abstract: The soluble form of the migration inhibitory factor receptor cluster of differentiation 74 (sCD74) has previously been shown to be elevated during the development of acute lung injury (ALI) in mice. However, the biological role… read more here.
Keywords: factor; nuclear factor; cluster differentiation; factor signaling ... See more keywords
Growth factor signaling predicts therapy resistance mechanisms and defines neuroblastoma subtypes
Sign Up to like & getrecommendations! Published in 2021 at "Oncogene"
DOI: 10.1038/s41388-021-02018-7
Abstract: Neuroblastoma (NB) has a low frequency of recurrent mutations compared to other cancers, which hinders the development of targeted therapies and novel risk stratification strategies. Multikinase inhibitors have shown potential in treating high-risk NB, but… read more here.
Keywords: epo ngf; growth factor; factor signaling; growth ... See more keywords
Chronic Binge Alcohol-Associated Differential Brain Region Modulation of Growth Factor Signaling Pathways and Neuroinflammation in Simian Immunodeficiency Virus-Infected Male Macaques.
Sign Up to like & getrecommendations! Published in 2019 at "Alcohol and alcoholism"
DOI: 10.1093/alcalc/agz056
Abstract: AIMS Microarray analysis of hippocampal tissue from chronic binge alcohol (CBA)-administered, simian immunodeficiency virus (SIV)-infected male macaques identified altered immune response and neurogenesis as potential mechanisms underlying cognitive deficits in macaques. This study investigated the… read more here.
Keywords: growth factor; factor signaling; brain; expression ... See more keywords
Neuronal fibroblast growth factor 22 signaling during development, but not in adults, is involved in anhedonia
Sign Up to like & getrecommendations! Published in 2019 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001399
Abstract: Growth factor signaling in the brain is implicated in many neuropsychiatric disorders, including depression, autism, and epilepsy. Fibroblast growth factor 22 is a growth factor that regulates excitatory synapse development and neurogenesis in the brain.… read more here.
Keywords: growth factor; factor signaling; growth; fibroblast growth ... See more keywords
Growth factor signaling alters the morphology of the zebrafish ethmoid plate
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Anatomy"
DOI: 10.1111/joa.12592
Abstract: Craniofacial development relies on coordinated tissue interactions that allow for patterning and growth of the face. We know a priori that the Wingless, fibroblast growth factor, Hedgehog and transforming growth factor‐beta growth factor signaling pathways… read more here.
Keywords: growth factor; factor signaling; growth; ethmoid plate ... See more keywords
Reprogramming Interferon Regulatory Factor Signaling in Cardiometabolic Diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Physiology"
DOI: 10.1152/physiol.00038.2016
Abstract: Interferon regulatory factors (IRFs) are evolutionarily conserved proteins expressed not only in immune cells but also in other tissues and organs outside the immune system. In this review, we discuss mechanisms responsible for IRF-mediated innate… read more here.
Keywords: cardiometabolic diseases; interferon regulatory; reprogramming interferon; regulatory factor ... See more keywords
Targeting Epsins to Inhibit Fibroblast Growth Factor Signaling While Potentiating Transforming Growth Factor-β Signaling Constrains Endothelial-to-Mesenchymal Transition in Atherosclerosis
Sign Up to like & getrecommendations! Published in 2023 at "Circulation"
DOI: 10.1161/circulationaha.122.063075
Abstract: Background: Epsin endocytic adaptor proteins are implicated in the progression of atherosclerosis; however, the underlying molecular mechanisms have not yet been fully defined. In this study, we determined how epsins enhance endothelial-to-mesenchymal transition (EndoMT) in… read more here.
Keywords: growth; atherosclerosis; growth factor; factor signaling ... See more keywords