Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23477
Abstract: Aberrant alternative splicing (AS) profoundly affects tumorigenesis and cancer progression. Serine/arginine‐rich splicing factor 3 (SRSF3) regulates the AS of precursor mRNAs and acts as a proto‐oncogene in many tumors, but its function and potential mechanisms… read more here.
Keywords: cervical cancer; ddx5; srsf3; factor srsf3 ... See more keywords
The splicing factor SRSF3 is functionally connected to the nuclear RNA exosome for intronless mRNA decay
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-31078-1
Abstract: The RNA exosome fulfills important functions in the processing and degradation of numerous RNAs species. However, the mechanisms of recruitment to its various nuclear substrates are poorly understood. Using Epstein-Barr virus mRNAs as a model,… read more here.
Keywords: rna exosome; nuclear rna; splicing factor; mrna decay ... See more keywords