Analysis of FcγR-Dependent Agonism of Antibodies Specific for Receptors of the Tumor Necrosis Factor (TNF) Receptor Superfamily (TNFRSF).
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DOI: 10.1007/978-1-0716-1130-2_6
Abstract: In vivo research of the last decade revealed that the anchoring of antitumor necrosis factor (TNF) receptor superfamily (TNFRSF) receptor antibodies to cell-expressed Fcγ receptors (FcγR) can be of decisive relevance for their receptor-stimulatory activity.… read more here.
Keywords: superfamily tnfrsf; receptor superfamily; factor tnf; receptor ... See more keywords
Celecoxib prevents tumor necrosis factor-α (TNF-α)-induced cellular senescence in human chondrocytes
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DOI: 10.1080/21655979.2021.2003661
Abstract: ABSTRACT Osteoarthritis (OA) is a cartilage degenerative disease commonly observed in the elderly population and significantly impacts the normal life of OA patients. It has been reported that the development of pathological cell senescence in… read more here.
Keywords: senescence; tnf induced; tnf; tumor necrosis ... See more keywords
Spondyloarthritis: Matrix Metalloproteinasesas Biomarkers of Pathogenesis and Response to Tumor Necrosis Factor (TNF) Inhibitors
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DOI: 10.3390/ijms18040830
Abstract: The term spondyloarthritis (SpA) is used to describe a group of multifactorial chronic inflammatory diseases characterized by a predisposing genetic background and clinical manifestations typically involving the sacroiliac joint. The absence of pathognomonic clinical and/or… read more here.
Keywords: tnf; response; spa; factor tnf ... See more keywords
Characterization of the Involvement of Tumour Necrosis Factor (TNF)-α-Stimulated Gene 6 (TSG-6) in Ischemic Brain Injury Caused by Middle Cerebral Artery Occlusion in Mouse
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DOI: 10.3390/ijms24065800
Abstract: The identification of novel targets to modulate the immune response triggered by cerebral ischemia is crucial to promote the development of effective stroke therapeutics. Since tumour necrosis factor (TNF)-α-stimulated gene 6 (TSG-6), a hyaluronate (HA)-binding… read more here.
Keywords: necrosis factor; tsg; brain; tumour necrosis ... See more keywords
Focus on Anti-Tumour Necrosis Factor (TNF)-α-Related Autoimmune Diseases
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DOI: 10.3390/ijms24098187
Abstract: Anti-tumour necrosis factor (TNF)-α agents have been increasingly used to treat patients affected by inflammatory bowel disease and dermatological and rheumatologic inflammatory disorders. However, the widening use of biologics is related to a new class… read more here.
Keywords: necrosis factor; tnf; autoimmune diseases; tumour necrosis ... See more keywords