Articles with "factor vii" as a keyword



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Topical application of recombinant activated factor VII during cesarean delivery for placenta previa

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Published in 2017 at "American Journal of Obstetrics and Gynecology"

DOI: 10.1016/j.ajog.2017.02.024

Abstract: BACKGROUND: During cesarean delivery in patients with placenta previa, hemorrhaging after removal of the placenta is often challenging. In this condition, the extraordinarily high concentration of tissue factor at the placenta site may constitute a… read more here.

Keywords: factor vii; activated factor; placenta; factor ... See more keywords
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Prostate surgery in severe congenital factor VII deficiency: A case report

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Published in 2019 at "Urology Case Reports"

DOI: 10.1016/j.eucr.2018.09.024

Abstract: Congenital factor VII (FVII) deficiency is an autosomal recessive disorder with an estimated prevalence of 1/500,000 individuals without ethnic or gender predilection, the gene for factor VII is found on chromosome 13, adjacent to the… read more here.

Keywords: vii deficiency; factor; factor vii; congenital factor ... See more keywords
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Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs).

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Published in 2018 at "Thrombosis research"

DOI: 10.1016/j.thromres.2017.11.012

Abstract: The circulating zymogen form of Factor VII activating protease (FSAP) can be activated by histones and nucleosomes in vivo. These cell-death-associated nuclear factors are also actively extruded into the extracellular space by neutrophils through a… read more here.

Keywords: protease fsap; activating protease; factor vii; neutrophil extracellular ... See more keywords
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Molecular View into Preferential Binding of the Factor VII Gla Domain to Phosphatidic Acid.

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Published in 2022 at "Biochemistry"

DOI: 10.1021/acs.biochem.2c00266

Abstract: Factor VII (FVII) is a serine protease with a key role in initiating the coagulation cascade. It is part of a family of vitamin K-dependent clotting proteins, which require vitamin K for formation of their… read more here.

Keywords: binding; gla domain; factor vii; phosphatidic acid ... See more keywords
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A factor VII-based method for the prediction of anticoagulant response to warfarin

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-30516-4

Abstract: Warfarin dosing methods based on existing models for warfarin and the international normalised ratio (INR) give biased maintenance dose predictions at the upper and lower quantiles of dose requirements. The aim of this work is… read more here.

Keywords: inr; factor vii; warfarin; method ... See more keywords
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Identification of two different coagulation phenotypes in people living with HIV with undetectable viral replication

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-83731-x

Abstract: Altered coagulation has been reported in people living with HIV (PLWH) with ongoing viral replication and may predispose to cardiovascular diseases. However, less is known about coagulation in PLWH with undetectable viral replication. In a… read more here.

Keywords: coagulation; factor vii; viral replication; undetectable viral ... See more keywords
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Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding.

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Published in 2021 at "Thrombosis and haemostasis"

DOI: 10.1055/a-1450-8568

Abstract: Clinical parameters have been extensively studied in factor (F) VII deficiency, but the knowledge of molecular mechanisms of this disease is scarce. We report on three probands with intracranial bleeds at early age, one of… read more here.

Keywords: fvii; molecular characterization; factor vii; characterization two ... See more keywords
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Interleukin 10, but not tumor necrosis factor-alpha, gene variations are associated with factor VII inhibitor development.

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Published in 2023 at "Laboratory medicine"

DOI: 10.1093/labmed/lmad026

Abstract: OBJECTIVE Development of alloantibodies against coagulation factor VII (FVII) is the main therapeutic challenge in severe congenital FVII deficiency. About 7% of patients with severe congenital FVII deficiency develop an inhibitor against FVII. In this… read more here.

Keywords: factor vii; development; factor; inhibitor development ... See more keywords
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Off-label Use of Recombinant Activated Factor VII for Cardiac Surgical Bleeding.

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Published in 2023 at "Anesthesiology"

DOI: 10.1097/aln.0000000000004569

Abstract: Recombinant activated factor VII has been widely used in an off-label manner for cardiac surgical bleeding. Recent reports have administered recombinant activated factor VII earlier in the course of bleeding and at lower doses than… read more here.

Keywords: cardiac surgical; recombinant activated; activated factor; factor vii ... See more keywords
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Novel IVS7+1G>T mutation of life-threatening congenital factor VII deficiency in neonates

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Published in 2019 at "Medicine"

DOI: 10.1097/md.0000000000017360

Abstract: Abstract In neonates, congenital factor VII deficiency (FVIID) is characterized by central nervous system bleeding and gastrointestinal hemorrhage, often resulting in poor prognosis and high mortality. To improve understanding of FVIID in neonates in Asia,… read more here.

Keywords: factor; vii deficiency; fvii; factor vii ... See more keywords
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Paradoxical massive pulmonary thromboembolism in a postpartum woman with factor VII deficiency with bleeding tendency: A case report

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Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000033437

Abstract: Rationale: Factor VII (FVII) deficiency is an inherited bleeding disorder, and women with FVII deficiency are at risk of gynecological bleeding and postpartum hemorrhage. There have been no reports of pulmonary embolism in a postpartum… read more here.

Keywords: postpartum; fvii deficiency; massive pulmonary; factor vii ... See more keywords