Knockout of von Willebrand factor in Zebrafish by CRISPR/Cas9 mutagenesis
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Haematology"
DOI: 10.1111/bjh.15910
Abstract: mutations associated with ibrutinib resistance in Waldenstrom macroglobulinemia. Blood, 129, 2519–2525. Yang, G., Zhou, Y., Liu, X., Xu, L., Cao, Y., Manning, R.J., Patterson, C.J., Buhrlage, S.J., Gray, N., Tai, Y.T., Anderson, K.C., Hunter, Z.R.… read more here.
Keywords: crispr cas9; knockout von; zebrafish crispr; von willebrand ... See more keywords
Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-02-765206
Abstract: Deficiency of factor X (F10) in humans is a rare bleeding disorder with a heterogeneous phenotype and limited therapeutic options. Targeted disruption of F10 and other common pathway factors in mice results in embryonic/neonatal lethality… read more here.
Keywords: genome editing; editing factor; f10; common pathway ... See more keywords