Discovery of Small Molecules Targeting the Synergy of Cardiac Transcription Factors GATA4 and NKX2-5.
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DOI: 10.1021/acs.jmedchem.7b00816
Abstract: Transcription factors are pivotal regulators of gene transcription, and many diseases are associated with the deregulation of transcriptional networks. In the heart, the transcription factors GATA4 and NKX2-5 are required for cardiogenesis. GATA4 and NKX2-5… read more here.
Keywords: transcription; factors gata4; small molecules; transcription factors ... See more keywords