Short-lived neutral FMN and FAD semiquinones are transient intermediates in cryo-reduced yeast NADPH-cytochrome P450 reductase.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.108080
Abstract: The electron configuration of flavin cofactors, FMN and FAD, is a critical factor governing the reactivity of NADPH-cytochrome P450 reductase (CPR). The current view of electron transfer by the mammalian CPR, based on equilibrium redox… read more here.
Keywords: nadph cytochrome; fmn fad; fad; electron ... See more keywords
Crystal structure of oleate hydratase from Stenotrophomonas sp. KCTC 12332 reveals conformational plasticity surrounding the FAD binding site.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.220
Abstract: Unsaturated fatty acids are toxic to various bacteria, causing their death or growth inhibition. To prevent this toxicity, unsaturated fatty acids should be converted into saturated fatty acids via hydrogenation reaction, which is the complete… read more here.
Keywords: fad; structure; oleate hydratase; kctc 12332 ... See more keywords
FAD Regulates CRYPTOCHROME Protein Stability and Circadian Clock in Mice.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.03.041
Abstract: The circadian clock generates biological rhythms of metabolic and physiological processes, including the sleep-wake cycle. We previously identified a missense mutation in the flavin adenine dinucleotide (FAD) binding pocket of CRYPTOCHROME2 (CRY2), a clock protein that… read more here.
Keywords: protein; regulates cryptochrome; circadian clock; fad ... See more keywords
Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer’s disease model mice
Sign Up to like & getrecommendations! Published in 2021 at "Current Biology"
DOI: 10.1016/j.cub.2021.05.039
Abstract: Not much is known about how the dentate gyrus (DG) and hippocampal CA3 networks, critical for memory and spatial processing, malfunction in Alzheimer's disease (AD). While studies of associative memory deficits in AD have focused… read more here.
Keywords: alzheimer disease; fad; model mice; mice ... See more keywords
Emotion dysregulation as a correlate of food and alcohol disturbance in undergraduate students.
Sign Up to like & getrecommendations! Published in 2020 at "Eating behaviors"
DOI: 10.1016/j.eatbeh.2020.101409
Abstract: Disordered eating behaviors (e.g., binge eating, food restriction, self-induced vomiting, and laxative use) as well as alcohol use and related issues are prevalent in undergraduate students and are often comorbid with one another. Recently, the… read more here.
Keywords: emotion dysregulation; dysregulation; undergraduate students; food ... See more keywords
Characteristics of membrane-bound fatty acid desaturase (FAD) genes in Brassica napus L. and their expressions under different cadmium and salinity stresses
Sign Up to like & getrecommendations! Published in 2019 at "Environmental and Experimental Botany"
DOI: 10.1016/j.envexpbot.2019.02.016
Abstract: Abstract The membrane-bound fatty acid desaturases (FADs) play vital roles in regulating plant fatty acid (FA) compositions which directly affect oil quality in rapeseed (Brassica napus L.). In the present study, a total of 68… read more here.
Keywords: fad genes; fad; membrane bound; bound fatty ... See more keywords
Biometric Alterations of Mouse Embryonic Eye Structures Due to Short-Term Folic Acid Deficiency
Sign Up to like & getrecommendations! Published in 2019 at "Current Eye Research"
DOI: 10.1080/02713683.2018.1545911
Abstract: ABSTRACT Purpose: Folic acid (FA) is an essential nutrient for normal embryonic development. FA deficiency (FAD) in maternal diet increases the risk of several defects among the progeny, especially, neural tube defects. The eye begins… read more here.
Keywords: folic acid; term; short term; fad ... See more keywords
Evolution of Linoleic Acid Biosynthesis Paved the Way for Ecological Success of Termites
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msad087
Abstract: Abstract Termites are dominant animals of tropical terrestrial ecosystems. Their success is due to their eusocial organization as well as their ability to digest dead plant tissues. While being extremely abundant, the termite diet is… read more here.
Keywords: biosynthesis; success; success termites; fad ... See more keywords
Identification of a novel deFADding activity in human, yeast and bacterial 5′ to 3′ exoribonucleases
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac617
Abstract: Abstract Identification of metabolite caps including FAD on the 5′ end of RNA has uncovered a previously unforeseen intersection between cellular metabolism and gene expression. To understand the function of FAD caps in cellular physiology,… read more here.
Keywords: identification novel; fad cap; defadding activity; fad ... See more keywords
What’s not to like about evidence-based management: a hyper-rational fad?
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Organizational Analysis"
DOI: 10.1108/ijoa-06-2020-2278
Abstract: Purpose A topic currently receiving significant academic and practitioner attention is called evidence-based management. The purpose of this paper is to suggest that this approach is sometimes over-sold and may be a fad. Additionally, evidence-based… read more here.
Keywords: based management; paper; evidence; fad ... See more keywords
Effect of drying method on the production of in vitro short-chain fatty acids and histone deacetylase mediation of cocoa pod husk.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food science"
DOI: 10.1111/1750-3841.16309
Abstract: We evaluated the effect of cocoa pod husk (CPH) processing (microwave [MW], forced-air drying [FAD], and FAD plus extrusion [FAD-E]), and in vitro gastrointestinal digestion on the in vitro human colonic fermentation metabolism, in vitro… read more here.
Keywords: pod husk; cocoa pod; chain fatty; cocoa ... See more keywords