Mutations in Genes Encoding 23S rRNA and FadD32 May be Associated with Linezolid Resistance in Mycobacteroides abscessus.
Sign Up to like & getrecommendations! Published in 2023 at "Microbial drug resistance"
DOI: 10.1089/mdr.2022.0068
Abstract: Linezolid is one of the antibiotics used to treat the Mycobacteroides abscessus infection. However, linezolid-resistance mechanisms of this organism are not well understood. The objective of this study was to identify possible linezolid-resistance determinants in… read more here.
Keywords: mycobacteroides abscessus; linezolid resistance; resistance; 23s rrna ... See more keywords
In Silico Drug Repurposing Approach: Investigation of Mycobacterium tuberculosis FadD32 Targeted by FDA-Approved Drugs
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030668
Abstract: Background: Despite the enormous efforts made towards combating tuberculosis (TB), the disease remains a major global threat. Hence, new drugs with novel mechanisms against TB are urgently needed. Fatty acid degradation protein D32 (FadD32) has… read more here.
Keywords: fda approved; drug; tuberculosis; mycobacterium ... See more keywords