Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells
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DOI: 10.3390/antibiotics12020415
Abstract: Polymyxins are last-line antibiotics for the treatment of Gram-negative ‘superbugs’. However, nephrotoxicity can occur in up to 60% of patients administered intravenous polymyxins. The mechanisms underpinning nephrotoxicity remain unclear. To understand polymyxin-induced nephrotoxicity, human renal… read more here.
Keywords: faddi 251; tubular cells; transcriptomic responses; 251 faddi ... See more keywords