Identification of a functional FADS1 3'UTR variant associated with erythrocyte n-6 polyunsaturated fatty acids levels.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2018.07.012
Abstract: BACKGROUND Blood polyunsaturated fatty acid (PUFA) levels are determined by diet and by endogenous synthesis via Δ5- and Δ6-desaturases (encoded by the FADS1 and FADS2 genes, respectively). Genome-wide association studies have reported associations between FADS1-FADS2… read more here.
Keywords: polyunsaturated fatty; fads1 fads2; variant; fads1 utr ... See more keywords
FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Epigenetics"
DOI: 10.1186/s13148-018-0545-5
Abstract: BackgroundGenome-wide association studies (GWASs) have shown that genetic variants are important determinants of free fatty acid levels. The mechanisms underlying the associations between genetic variants and free fatty acid levels are incompletely understood. Here, we… read more here.
Keywords: fatty acid; fads1 fads2; expression; gene ... See more keywords
FADS1 and FADS2 Gene Polymorphisms Modulate the Relationship of Omega-3 and Omega-6 Fatty Acid Plasma Concentrations in Gestational Weight Gain: A NISAMI Cohort Study
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14051056
Abstract: The polymorphisms of fatty acid desaturase genes FADS1 and FADS2 have been associated with an increase in weight gain. We investigated FADS1 and FADS2 gene polymorphisms and the relation between ω-3 and ω-6 fatty acid… read more here.
Keywords: weight gain; weight; fatty acid; fads1 fads2 ... See more keywords