PARP inhibitor Olaparib increases the sensitization to radiotherapy in FaDu cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14929
Abstract: Radioresistance causes a major problem for improvement of outcomes of patients treated with radiation. Targeting for DNA repair deficient mechanisms is a hallmark of sensitization to resistance. We tested whether Olaparib, a (poly) ADP‐ribose polymerase… read more here.
Keywords: fadu cells; fadu; parp inhibitor; olaparib ... See more keywords
Psoralen as a Photosensitizers for Photodynamic Therapy by Means of In Vitro Cherenkov Light
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315233
Abstract: Possible enhancements of DNA damage with light of different wavelengths and ionizing radiation (Rhenium-188—a high energy beta emitter (Re-188)) on plasmid DNA and FaDu cells via psoralen were investigated. The biophysical experimental setup could also… read more here.
Keywords: dna; cherenkov light; plasmid dna; dna damage ... See more keywords
Novel Homo-Bivalent and Polyvalent Compounds Based on Ligustrazine and Heterocyclic Ring as Anticancer Agents
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24244505
Abstract: Bivalent and polyvalent inhibitors can be used as antitumor agents. In this experiment, eight ligustrazine dimers and seven ligustrazine tetramers linked by alkane diamine with different lengths of carbon chain lengths were synthesized. After screening… read more here.
Keywords: fadu cells; novel homo; bivalent polyvalent; polyvalent ... See more keywords
Biochanin-A induces apoptosis and suppresses migration in FaDu human pharynx squamous carcinoma cells.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology reports"
DOI: 10.3892/or.2017.5953
Abstract: The aim of the present study was to investigate biochanin-A-induced anticancer effects and their cellular signaling pathway in FaDu pharyngeal squamous carcinoma cells. Biochanin-A induced cell death through increased cytotoxicity of FaDu cells in a… read more here.
Keywords: squamous carcinoma; fadu cells; biochanin; carcinoma cells ... See more keywords
Exosomes from M2 macrophages promoted glycolysis in FaDu cells by inhibiting PDLIM2 expression to stabilize PFKL.
Sign Up to like & getrecommendations! Published in 2022 at "Neoplasma"
DOI: 10.4149/neo_2022_220426n455
Abstract: Laryngeal squamous cell carcinoma (LSCC) is one of the most prevalent malignant diseases worldwide. LSCC patients suffer from a severe decline in life quality, due to the essential roles of the larynx in basic functions… read more here.
Keywords: cell; fadu cells; expression; glycolysis ... See more keywords