Faecal immunochemical test for patients with ‘high-risk’ bowel symptoms: a large prospective cohort study and updated literature review
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DOI: 10.1038/s41416-021-01653-x
Abstract: Background We evaluated whether faecal immunochemical testing (FIT) can rule out colorectal cancer (CRC) among patients presenting with ‘high-risk’ symptoms requiring definitive investigation. Methods Three thousand five hundred and ninety-six symptomatic patients referred to the… read more here.
Keywords: literature review; updated literature; high risk; specificity ... See more keywords
How a faecal immunochemical test screening programme changes annual colorectal cancer incidence rates: an Italian intention-to-screen study.
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DOI: 10.1038/s41416-022-01813-7
Abstract: BACKGROUND This study aimed to evaluate the effectiveness of a biennial faecal immunochemical test (FIT) screening programme in reducing annual colorectal cancer (CRC) incidence in its dynamic target population. METHODS The target population included over… read more here.
Keywords: immunochemical test; incidence; faecal immunochemical; cancer ... See more keywords
Diagnostic accuracy of a quantitative faecal immunochemical test vs. symptoms suspected for colorectal cancer in patients referred for colonoscopy
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DOI: 10.1080/00365521.2019.1708965
Abstract: Abstract Objective: Determine diagnostic accuracy of a quantitative faecal immunochemical haemoglobin test (QuikRead go® FIT, Orion Diagnostica Oy) in symptomatic patients referred for colonoscopy, at various cut-offs and for one or two tests. Methods: Patients… read more here.
Keywords: faecal immunochemical; diagnostic accuracy; referred colonoscopy; quantitative faecal ... See more keywords
O136 An observational cohort study of replicate faecal immunochemical tests in symptomatic two-week wait patients
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DOI: 10.1093/bjs/znad101.136
Abstract: Triage of patients with suspected colorectal cancer (CRC) utilises a single faecal immunochemical test (FIT) at a defined threshold. Limited evidence exists regarding whether replicate FIT improves the positive and negative predictive value in symptomatic… read more here.
Keywords: faecal immunochemical; fit; replicate fit; double positive ... See more keywords
Colorectal cancer prevalence in faecal immunochemical test non-returners: potential for health inequality in symptomatic referral pathways
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DOI: 10.1093/bjsopen/zrae119
Abstract: Abstract Background This study aimed to describe the faecal immunochemical test non-return rate of those referred with high-risk symptoms of colorectal cancer from primary care, and the clinical outcomes of the ‘non-returners’. Methods From January… read more here.
Keywords: immunochemical test; colorectal cancer; non returners; faecal immunochemical ... See more keywords
Diagnostic accuracy of the faecal immunochemical test and volatile organic compound analysis in detecting colorectal polyps: meta-analysis
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DOI: 10.1093/bjsopen/zrae154
Abstract: Abstract Background For the early detection of colorectal cancer, it is important to identify the premalignant lesions to prevent cancer development. Non-invasive testing methods such as the faecal immunochemical test are well established for the… read more here.
Keywords: immunochemical test; faecal immunochemical; volatile organic; analysis ... See more keywords
Faecal immunochemical test-based colorectal cancer screening in Mexico: an initial experience
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DOI: 10.1093/fampra/cmz078
Abstract: Abstract Background In middle-income countries, the burden of colorectal cancer (CRC) is increasing in parallel with resources for diagnosis and treatment. There is a potential benefit of CRC screening programs in Mexico. Objective Since there… read more here.
Keywords: screening programs; faecal immunochemical; colorectal cancer; test ... See more keywords
False-negative rate cannot be reduced by lowering the haemoglobin concentration cut-off in colorectal cancer screening using faecal immunochemical test
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DOI: 10.1097/cej.0000000000000281
Abstract: The aim of this study was to analyse false-negative (FN) results of the faecal immunochemical test (FIT) and its determinants in a colorectal cancer screening programme in Catalonia. We carried out a cross-sectional study among… read more here.
Keywords: faecal immunochemical; colorectal cancer; false negative; immunochemical test ... See more keywords
Diagnostic accuracy of point of care faecal immunochemical testing using a portable high‐speed quantitative analyser for diagnosis in 2‐week wait patients
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DOI: 10.1111/codi.15780
Abstract: Laboratory‐based faecal immunochemical testing (FIT) is the gold standard for detecting the presence of blood in the stool. The aim was to perform a diagnostic accuracy study to confirm if a point of care (POC)… read more here.
Keywords: faecal immunochemical; point care; diagnostic accuracy; immunochemical testing ... See more keywords
Finding the needle in the haystack: the diagnostic accuracy of the faecal immunochemical test for colorectal cancer in younger symptomatic patients
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DOI: 10.1111/codi.15786
Abstract: Detection of early onset colorectal cancer is challenging, and remains a rare diagnosis amongst younger people with gastrointestinal symptoms. We investigated whether faecal immunochemical testing (FIT) could identify younger patients at higher risk of colorectal… read more here.
Keywords: finding needle; faecal immunochemical; colorectal cancer; needle haystack ... See more keywords
The use of the faecal immunochemical test during the COVID‐19 pandemic to triage urgent colorectal cancer referrals
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DOI: 10.1111/codi.16120
Abstract: During the first wave of the COVID‐19 pandemic in 2020, elective gastrointestinal endoscopy services were abbreviated for fear of viral transmission. However, urgent suspected colorectal cancer (CRC) referrals continued. Serendipitously, a national study suggested that… read more here.
Keywords: colorectal cancer; immunochemical test; faecal immunochemical; covid pandemic ... See more keywords