Peptoid‐Peptide Hybrid Analogs of the Enterococcus faecalis Fsr Auto‐Inducing Peptide (AIP) Reveal Crucial Structure‐Activity Relationships
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200527
Abstract: As multidrug‐resistant bacteria become a more pressing risk to human health, alternate approaches to treating bacterial infections are being increasingly investigated. Enterococcus faecalis is an opportunistic pathogen responsible for a large percentage of secondary enterococci… read more here.
Keywords: peptide hybrid; faecalis fsr; hybrid analogs; enterococcus faecalis ... See more keywords
Rational Design of Potent Activators and Inhibitors of the Enterococcus faecalis Fsr Quorum Sensing Circuit.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical biology"
DOI: 10.1021/acschembio.8b00610
Abstract: The increasing rate of resistance development to conventional antibiotics by bacteria necessitates the identification of alternative treatment possibilities that can reduce the ability of bacteria to adapt. Enterococcus faecalis remains the leading cause of clinical… read more here.
Keywords: potent activators; activators inhibitors; quorum sensing; enterococcus faecalis ... See more keywords