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Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31152
Abstract: Development of intestinal failure–associated liver disease (IFALD) is a common complication of long‐term parenteral nutrition (PN) in children and adults. The molecular and cellular mechanisms and the phases of IFALD are now being delineated. Components…
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Keywords:
failure associated;
associated liver;
intestinal failure;
new insights ... See more keywords
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Published in 2020 at "Hepatology International"
DOI: 10.1007/s12072-020-10048-8
Abstract: Premature infants and children with intestinal failure (IF) or short bowel syndrome are susceptible to intestinal failure-associated liver disease (IFALD, previously referred to as parenteral nutrition-associated liver disease, or PNALD). IFALD in children is characterized…
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Keywords:
associated liver;
liver disease;
failure associated;
intestinal failure ... See more keywords
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Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.08.006
Abstract: Although the pathogenesis of intestinal failure (IF)-associated liver disease (IFALD) is uncertain, IF-associated cholestasis mediated by the combination of intestinal injury and parenteral nutrition (PN) can lead to disturbed hepatocyte bile acids (BA) homeostasis and…
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Keywords:
failure associated;
bile acids;
disease;
associated liver ... See more keywords
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Published in 2017 at "Transplantation"
DOI: 10.1097/01.tp.0000521384.16748.d9
Abstract: Objectives of the study: Children with splenomegaly and portal hypertension due to primary liver disease demonstrate presence of gastrooesophageal varices (GOV) on oesophago-gastroduodenoscopy (OGD). Intestinal failure – associated liver disease (IFALD) is a secondary liver…
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Keywords:
failure associated;
liver;
children splenomegaly;
intestinal failure ... See more keywords
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Published in 2019 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000000620
Abstract: Purpose of review The current review provides a summary of available lipid products and discusses current literature and the limitations to the use of various lipid products for treatment and prevention of intestinal failure-associated liver…
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Keywords:
intestinal failure;
fish oil;
lipid emulsions;
failure associated ... See more keywords
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Published in 2018 at "Journal of Parenteral and Enteral Nutrition"
DOI: 10.1177/0148607116677048
Abstract: BACKGROUND Deficiency of choline, a required nutrient, is related to intestinal failure-associated liver disease (IFALD). Therefore, we aimed to investigate the effects of choline supplementation on IFALD and the underlying mechanisms. METHODS Male Sprague-Dawley rats…
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Keywords:
choline;
failure associated;
group;
associated liver ... See more keywords
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Published in 2019 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v7.i13.1717
Abstract: BACKGROUND Benzbromarone is a uricosuric agent that reduces proximal tubular reabsorption of uric acid. Because of hepatotoxicity, it has been withdrawn from the market in Europe. Recently, some benefit-risk assessments of benzbromarone suggest that benzbromarone…
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Keywords:
failure associated;
liver failure;
case;
associated benzbromarone ... See more keywords
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Published in 2018 at "Nutrients"
DOI: 10.3390/nu10060664
Abstract: Intestinal failure-associated liver disease (IFALD) is a threatening complication for children on long-term parenteral nutrition because of intestinal failure. When progressive and intractable, it may jeopardize intestinal rehabilitation and lead to combined liver and intestinal…
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Keywords:
failure associated;
associated liver;
prevention treatment;
intestinal failure ... See more keywords