Management of heart failure with reduced ejection fraction in Europe: design of the ARIADNE registry
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DOI: 10.1002/ehf2.12569
Abstract: The introduction of sacubitril/valsartan (an angiotensin receptor–neprilysin inhibitor) is likely to change the approach to the management of patients with chronic heart failure with reduced ejection fraction (HFrEF). The Assessment of Real Life Care–Describing European… read more here.
Keywords: heart; heart failure; management; reduced ejection ... See more keywords
Patient factors associated with titration of medical therapy in patients with heart failure with reduced ejection fraction: data from the QUALIFY international registry
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DOI: 10.1002/ehf2.13237
Abstract: Failure to prescribe key medicines at evidence‐based doses is associated with increased mortality and hospitalization for patients with Heart Failure with reduced Ejection Fraction (HFrEF). We assessed titration patterns of guideline‐recommended HFrEF medicines internationally and… read more here.
Keywords: heart failure; reduced ejection; failure reduced; patients heart ... See more keywords
SGLT2i versus ARNI in heart failure with reduced ejection fraction: a systematic review and meta‐analysis
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DOI: 10.1002/ehf2.13313
Abstract: This study aimed to determine the effects of sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) in heart failure with reduced ejection fraction (HFrEF), compare the effect of SGLT2i with angiotensin receptor neprilysin inhibitor (ARNI), and find whether combination… read more here.
Keywords: ejection fraction; heart; heart failure; reduced ejection ... See more keywords
Neutrophils pro‐inflammatory and anti‐inflammatory cytokine release in patients with heart failure and reduced ejection fraction
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DOI: 10.1002/ehf2.13539
Abstract: Heart failure with reduced ejection fraction (HFrEF) is characterized by sub‐clinical inflammation. Changes in selected biomarkers of inflammation concomitant with the release of pro‐inflammatory and anti‐inflammatory cytokines by neutrophils have not been investigated in patients… read more here.
Keywords: ejection fraction; heart; heart failure; reduced ejection ... See more keywords
The benefits of the earlier use of sacubitril/valsartan in de novo heart failure with reduced ejection fraction patients
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DOI: 10.1002/ehf2.13940
Abstract: We evaluated the clinical outcomes and trajectory of cardiac reverse remodelling according to the timing of sacubitril/valsartan (Sac/Val) use in patients with heart failure (HF) with reduced ejection fraction (HFrEF). read more here.
Keywords: sacubitril valsartan; heart failure; failure reduced; heart ... See more keywords
Modified reverse shock index predicts early outcomes of heart failure with reduced ejection fraction
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DOI: 10.1002/ehf2.14031
Abstract: Increased blood pressure (BP) and decreased heart rate (HR) are signs of stabilization in patients admitted for acute HF. Changes in BP and HR during admission and their correlation with outcomes were assessed in hospitalized… read more here.
Keywords: heart failure; failure reduced; ejection fraction; heart ... See more keywords
Treatment response in recent‐onset heart failure with reduced ejection fraction: non‐ischaemic vs. ischaemic aetiology
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DOI: 10.1002/ehf2.14214
Abstract: In heart failure (HF) with reduced left ventricular ejection fraction (HFrEF), the prognosis appears better in non‐ischaemic than in ischaemic aetiology. Infrequent diagnostic work‐up for ischaemic heart disease (IHD) in HF is reported. In this… read more here.
Keywords: heart failure; non ischaemic; failure reduced; heart ... See more keywords
Microvascular complications in diabetes patients with heart failure and reduced ejection fraction—insights from the Beta‐blocker Evaluation of Survival Trial
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DOI: 10.1002/ejhf.1201
Abstract: The role of microvascular complications in the risk conferred by diabetes in heart failure with reduced ejection fraction (HFrEF) is unknown. read more here.
Keywords: heart; heart failure; microvascular complications; reduced ejection ... See more keywords
Medication dosing for heart failure with reduced ejection fraction — opportunities and challenges
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DOI: 10.1002/ejhf.1351
Abstract: Multiple drug classes have shown incremental benefits in heart failure with reduced ejection fraction. Most of these trials were designed to achieve specific doses of the investigational agent. Clinical practice guidelines recommend using the same… read more here.
Keywords: ejection fraction; heart; heart failure; reduced ejection ... See more keywords
Association between beta‐blocker use and mortality/morbidity in older patients with heart failure with reduced ejection fraction. A propensity score‐matched analysis from the Swedish Heart Failure Registry
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DOI: 10.1002/ejhf.1615
Abstract: Beta‐blockers reduce mortality and morbidity in heart failure (HF) with reduced ejection fraction (HFrEF). However, patients older than 80 years are poorly represented in randomized controlled trials. We assessed the association between beta‐blocker use and outcomes… read more here.
Keywords: heart; mortality morbidity; beta; heart failure ... See more keywords
Association between potassium level and outcomes in heart failure with reduced ejection fraction: a cohort study from the Swedish Heart Failure Registry
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DOI: 10.1002/ejhf.1757
Abstract: Hyperkalaemia and hypokalaemia are common in heart failure and associated with worse outcomes. However, the optimal potassium range is unknown. We sought to determine the optimal range of potassium in patients with heart failure and… read more here.
Keywords: potassium; heart; heart failure; reduced ejection ... See more keywords