LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "fak signaling" as a keyword



Photo from wikipedia

Plasma exosomes stimulate breast cancer metastasis through surface interactions and activation of FAK signaling

Sign Up to like & get
recommendations! Published in 2018 at "Breast Cancer Research and Treatment"

DOI: 10.1007/s10549-018-5043-0

Abstract: PurposeThe interaction between malignant cells and surrounding healthy tissues is a critical factor in the metastatic progression of breast cancer (BC). Extracellular vesicles, especially exosomes, are known to be involved in inter-cellular communication during cancer… read more here.

Keywords: cancer; fak signaling; plasma exosomes; breast cancer ... See more keywords
Photo by enchaxcreative from unsplash

ZNF32 induces anoikis resistance through maintaining redox homeostasis and activating Src/FAK signaling in hepatocellular carcinoma.

Sign Up to like & get
recommendations! Published in 2019 at "Cancer letters"

DOI: 10.1016/j.canlet.2018.09.033

Abstract: Tumor cells need to attain anoikis resistance to survive prior to metastasis making it a vital trait of malignancy. The molecular mechanism by which hepatocellular carcinoma (HCC) cells resist anoikis remains not fully understood. Here,… read more here.

Keywords: hcc; fak signaling; anoikis resistance; znf32 ... See more keywords
Photo by enchaxcreative from unsplash

Ibrutinib reverses IL-6-induced osimertinib resistance through inhibition of Laminin α5/FAK signaling

Sign Up to like & get
recommendations! Published in 2022 at "Communications Biology"

DOI: 10.1038/s42003-022-03111-7

Abstract: Osimertinib, a 3rd generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is the first-line standard-of-care for EGFR-mutant non-small cell lung cancer (NSCLC) patients, while acquired drug resistance will inevitably occur. Interleukin-6 (IL-6) is a… read more here.

Keywords: fak signaling; resistance; laminin fak; osimertinib resistance ... See more keywords
Photo by cdc from unsplash

Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer

Sign Up to like & get
recommendations! Published in 2017 at "Journal of Ovarian Research"

DOI: 10.1186/s13048-017-0358-8

Abstract: BackgroundMetastasis is the major cause of morbidity and mortality in patients with epithelial ovarian cancer (EOC), however the mechanisms that underline this process are poorly understood. Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa… read more here.

Keywords: fak signaling; cthrc1; eoc; integrin fak ... See more keywords
Photo from wikipedia

An Aqueous Extract of Herbal Medicine ALWPs Enhances Cognitive Performance and Inhibits LPS-Induced Neuroinflammation via FAK/NF-κB Signaling Pathways

Sign Up to like & get
recommendations! Published in 2018 at "Frontiers in Aging Neuroscience"

DOI: 10.3389/fnagi.2018.00269

Abstract: Recent studies have shown that Liuwei Dihuang pills (LWPs) can positively affect learning, memory and neurogenesis. However, the underlying molecular mechanisms are not understood. In the present study, we developed ALWPs, a mixture of Antler… read more here.

Keywords: medicine; lps induced; fak signaling; neuroinflammation ... See more keywords