Structure-based identification of novel FAK1 inhibitors using pharmacophore modeling, molecular dynamics, and MM/PBSA calculations
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DOI: 10.1038/s41598-025-23203-8
Abstract: Focal adhesion kinase 1 (FAK1) is a non-receptor tyrosine kinase involved in cancer metastasis and tumor progression. Due to its role in regulating cell migration and survival, FAK1 is considered a promising target for cancer… read more here.
Keywords: structure based; based identification; identification novel; fak1 ... See more keywords