Red blood cell exchange in treatment of severe cerebral P. falciparum malaria: A case report
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21667
Abstract: Introduction: Red blood cells exchange transfusion has been demonstrated to be helpful in treatment of sever P. falciparum malaria. However, no large scale randomized controlled trials have been completed to date and the CDC does… read more here.
Keywords: red blood; treatment; severe cerebral; falciparum malaria ... See more keywords
Hyper-diverse antigenic variation and resilience to transmission-reducing intervention in falciparum malaria
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-51468-6
Abstract: Intervention efforts against falciparum malaria in high-transmission regions remain challenging, with rapid resurgence typically following their relaxation. Such resilience co-occurs with incomplete immunity and a large transmission reservoir from high asymptomatic prevalence. Incomplete immunity relates… read more here.
Keywords: transmission; intervention; antigenic variation; falciparum malaria ... See more keywords
Probabilistic classification of late treatment failure in uncomplicated falciparum malaria
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-64830-z
Abstract: Distinguishing treatment failure (recrudescence) from reinfection in uncomplicated falciparum malaria is essential for characterising antimalarial treatment efficacy in malaria endemic areas. Classification of recrudescence versus reinfection is usually based on a comparison of parasite allelic… read more here.
Keywords: classification; treatment; treatment failure; falciparum malaria ... See more keywords
Antibodies against Plasmodium falciparum malaria at the molecular level
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Immunology"
DOI: 10.1038/s41577-019-0209-5
Abstract: Malaria is a vector-borne disease of global importance, with the vast majority of its life-threatening cases caused by infection with Plasmodium falciparum parasites. Repeated exposure to P. falciparum leads to naturally occurring immunity, but this… read more here.
Keywords: antibodies plasmodium; molecular level; plasmodium falciparum; falciparum malaria ... See more keywords
Delayed diagnosis of severe falciparum malaria in a patient presenting with acute gastroenteritis in West Texas
Sign Up to like & getrecommendations! Published in 2022 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2022.2049565
Abstract: Abstract Falciparum malaria is a life-threatening infection that affects both people in endemic areas and people who travel to endemic areas. Malaria in exceedingly rare in West Texas, but the initial recognition and prompt initiation… read more here.
Keywords: falciparum malaria; west texas; malaria; acute gastroenteritis ... See more keywords
HRP2/3 Mutation in Recrudescent Plasmodium falciparum Malaria Case Acquired in Ethiopia.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of travel medicine"
DOI: 10.1093/jtm/taaa196
Abstract: A 65-year-old Israeli working in Welkait, Ethiopia, not using malaria prophylaxis, developed fever. Malaria RDT was consistent with non-falciparum malaria (plasmodium LDH+/HRP-) but microscopy showed typical P. falciparum. HRP2/3 were negative by PCR. The patient… read more here.
Keywords: falciparum malaria; falciparum; hrp2 mutation; plasmodium ... See more keywords
Recrudescence of P.falciparum malaria in a migrant treated by tocilizumab.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of travel medicine"
DOI: 10.1093/jtm/taab043
Abstract: We report an atypical case of recrudescence of Plasmodium falciparum in a migrant with 4% parasitemia, 7 years after leaving endemic country. This case supports the hypothesis of recrudescence of a latent and persistent sub-microscopic parasitemia,… read more here.
Keywords: falciparum; migrant treated; recrudescence falciparum; falciparum malaria ... See more keywords
Increased imported severe Plasmodium falciparum malaria involving hyperparasitaemia (>10%) in a UK hospital following relaxation of COVID-19 restrictions compared to the pre-pandemic period
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Travel Medicine"
DOI: 10.1093/jtm/taac116
Abstract: Abstract We identified and compared patients diagnosed with Plasmodium falciparum malaria at a large hospital in London, UK prior to the COVID-19 pandemic versus following relaxation of COVID-19-associated restrictions. We found that parasitaemias, rates of… read more here.
Keywords: plasmodium falciparum; following relaxation; falciparum malaria; relaxation ... See more keywords
Expression of cleaved caspase‐3 in renal tubular cells in Plasmodium falciparum malaria patients
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DOI: 10.1111/nep.12715
Abstract: In Plasmodium falciparum malaria, the clinical manifestation of acute kidney injury (AKI) is commonly associated with acute tubular necrosis (ATN) in the kidney tissues. Renal tubular cells often exhibit various degrees of cloudy swelling, cell… read more here.
Keywords: expression cleaved; tubular cells; plasmodium falciparum; falciparum malaria ... See more keywords
pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02382-16
Abstract: ABSTRACT We present case histories of four patients treated with artemether-lumefantrine for falciparum malaria in UK hospitals in 2015 to 2016. Each subsequently presented with recurrent symptoms and Plasmodium falciparum parasitemia within 6 weeks of… read more here.
Keywords: treated artemether; artemether lumefantrine; treatment; plasmodium falciparum ... See more keywords
Ficolin-1 in pediatric Plasmodium falciparum malaria and its possible role in parasite clearance and anemia
Sign Up to like & getrecommendations! Published in 2025 at "Infection and Immunity"
DOI: 10.1128/iai.00194-25
Abstract: ABSTRACT Plasmodium falciparum malaria causes significant disease, especially in young children. A successful immune response to P. falciparum is a major determinant of clinical outcome. The ficolins are a family of lectins that act as… read more here.
Keywords: falciparum; role; falciparum malaria; ficolin ... See more keywords