FAM129B‐dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23295
Abstract: Incidence of melanoma continues to rise in the United States with ~100,000 new cases diagnosed in 2019. While the 5‐year survival rate of melanoma is 99% when localized, the rate of survival drops to 22.5%… read more here.
Keywords: melanoma; mutant melanoma; braf; melanoma cells ... See more keywords
Upregulation of FAM129B protects cardiomyocytes from hypoxia/reoxygenation‐induced injury by inhibiting apoptosis, oxidative stress, and inflammatory response via enhancing Nrf2/ARE activation
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23461
Abstract: Family with sequence similarity 129, member B (FAM129B) has been identified as a novel cytoprotective protein that facilitates the survival of detrimentally stimulated cells. However, whether FAM129B is involved in regulating cardiomyocyte survival after myocardial… read more here.
Keywords: fam129b; hypoxia reoxygenation; upregulation fam129b; injury ... See more keywords