Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma
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DOI: 10.1038/s41420-022-00984-9
Abstract: Family with sequence similarity 84, member B (FAM84B) is a significant copy number amplification gene in the 8q24.21 locus identified by our previous WGS study in esophageal squamous cell carcinoma (ESCC). However, its clinical relevance… read more here.
Keywords: expression; esophageal squamous; escc; cell ... See more keywords
FAM84B promotes prostate tumorigenesis through a network alteration
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DOI: 10.1177/1758835919846372
Abstract: Background: The aim of this study was to investigate the contributions of FAM84B in prostate tumorigenesis and progression. Methods: A FAM84B mutant with deletion of its HRASLS domain (ΔHRASLS) was constructed. DU145 prostate cancer (PC)… read more here.
Keywords: prostate tumorigenesis; hrasls; network; fam84b ... See more keywords
Upregulation of FAM84B during prostate cancer progression
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DOI: 10.18632/oncotarget.15168
Abstract: Although the FAM84B gene lies within chromosome 8q24, a locus frequently altered in prostate cancer (PC), its alteration during prostate tumorigenesis has not been well studied. We report here FAM84B upregulation in DU145 cell-derived prostate… read more here.
Keywords: fam84b; upregulation; primary pcs; prostate cancer ... See more keywords