Familial aggregation of major depressive disorder in an African‐American community
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DOI: 10.1002/da.22775
Abstract: African Americans (AAs) with major depressive disorder (MDD) experience more impairment and poorer treatment outcomes relative to Whites, yet are underrepresented in family studies of MDD. This is the first study to investigate the familial… read more here.
Keywords: depressive disorder; familial aggregation; major depressive; aggregation major ... See more keywords
Detecting Familial Aggregation.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7274-6_8
Abstract: In addition to characterizing the distribution of genetic features of populations (mutation and allele frequencies; measures of Hardy-Weinberg equilibrium), genetic epidemiology and statistical genetics aim to explore and define the role of genomic variation in… read more here.
Keywords: familial aggregation; question; genetics; disease ... See more keywords
Comorbidity and patterns of familial aggregation in attention-deficit/hyperactivity disorder and bipolar disorder in a family study of affective and anxiety spectrum disorders.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2020.08.017
Abstract: The aim of this study is to examine the familial aggregation of Attention-deficit/hyperactivity disorder (ADHD) and its cross-transmission with bipolar disorder (BD) in a community-based family study of mood spectrum disorders. A clinically-enriched community sample… read more here.
Keywords: familial aggregation; disorder; family; study ... See more keywords
Understanding the relationship between asthma and autism spectrum disorder: a population-based family and twin study
Sign Up to like & getrecommendations! Published in 2022 at "Psychological Medicine"
DOI: 10.1017/s0033291721005158
Abstract: Abstract Background There is some evidence that autism spectrum disorder (ASD) frequently co-occurs with immune-mediated conditions including asthma. We aimed to explore the familial co-aggregation of ASD and asthma using different genetically informed designs. Methods… read more here.
Keywords: familial aggregation; autism spectrum; asthma asd; spectrum disorder ... See more keywords
Familial Aggregation of Insomnia
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DOI: 10.1093/sleep/zsw053
Abstract: Study Objectives: There is little information about familial aggregation of insomnia; however, this type of information is important to (1) improve our understanding of insomnia risk factors and (2) to design more effective treatment and… read more here.
Keywords: risk; first degree; familial aggregation; aggregation insomnia ... See more keywords
Familial aggregation of focal seizure semiology in the Epilepsy Phenome/Genome Project
Sign Up to like & getrecommendations! Published in 2017 at "Neurology"
DOI: 10.1212/wnl.0000000000004052
Abstract: Objective: To improve phenotype definition in genetic studies of epilepsy, we assessed the familial aggregation of focal seizure types and of specific seizure symptoms within the focal epilepsies in families from the Epilepsy Phenome/Genome Project.… read more here.
Keywords: semiology; focal seizure; familial aggregation; aggregation focal ... See more keywords
Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies
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DOI: 10.1371/journal.pgen.1008490
Abstract: Despite genetics being accepted as the primary cause of familial aggregation for most diseases, it is still unclear whether afflicted families are likely to share a single highly penetrant rare variant, many minimally penetrant common… read more here.
Keywords: prs; familial aggregation; genetics; sequencing studies ... See more keywords
Case of Patient with AML with Complex Karyotype including Ultra-Rare t(4;8)(q32;q13), t(4;11)(q21;p15) and Familial Aggregation of Myeloid Malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina58010105
Abstract: We present a unique case of a young woman with acute myeloid leukemia (AML) with complex karyotype. The presence of the t(4;11)(q23;p15) is extremely rare in myeloid leukemias, while t(4;8)(q32;q13) has not yet been described… read more here.
Keywords: q32 q13; aml complex; myeloid; complex karyotype ... See more keywords
Familial aggregation of inflammatory bowel disease in India: prevalence, risks and impact on disease behavior
Sign Up to like & getrecommendations! Published in 2019 at "Intestinal Research"
DOI: 10.5217/ir.2018.00174
Abstract: Background/Aims Information about familial aggregation of inflammatory bowel disease (IBD) in Asia is limited. We aimed to analyze the prevalence and risk of familial IBD in an Indian cohort and compare familial and sporadic cases.… read more here.
Keywords: familial aggregation; prevalence; disease; familial ibd ... See more keywords