Establishment of an iPSC line (JSPHi001-A) from a patient with familial dilated cardiomyopathy and atrial fibrillation caused by LMNA missense mutation (c.1003C > T).
Sign Up to like & getrecommendations! Published in 2021 at "Stem cell research"
DOI: 10.1016/j.scr.2021.102349
Abstract: Peripheral blood mononuclear cells (PBMCs) were harvested and reprogramed to induced pluripotent stem cells (iPSCs) from a 46-year-old male patient with familial dilated cardiomyopathy and atrial fibrillation via a non-integrating system. A missense mutation in… read more here.
Keywords: atrial fibrillation; familial dilated; missense mutation; cardiomyopathy atrial ... See more keywords
A novel gene therapy for familial dilated cardiomyopathy based upon disruption of PP2A -- mAKAP-beta signalosomes
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733792
Abstract: Familial Dilated Cardiomyopathy (DCM) is a common inherited cause of heart failure characterized by progressive left ventricular dilatation and systolic dysfunction. Despite the discovery of novel genetic mutations causing DCM, the downstream mechanisms resulting in… read more here.
Keywords: makap; familial dilated; pp2a; physiology ... See more keywords
Teen pregnancy in the setting of familial dilated cardiomyopathy: a case report
Sign Up to like & getrecommendations! Published in 2022 at "BMC Pregnancy and Childbirth"
DOI: 10.1186/s12884-022-04427-2
Abstract: Background Women with pre-existing forms of familial cardiomyopathy are at increased risk for morbidity and mortality due to hemodynamic changes of pregnancy. There is a lack of consensus about the management and care for these… read more here.
Keywords: case report; pregnancy; dilated cardiomyopathy; familial dilated ... See more keywords