Familial gastrointestinal stromal tumors, lentigines, and café‐au‐lait macules associated with germline c‐kit mutation treated with imatinib
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DOI: 10.1111/ijd.13516
Abstract: Familial lentiginosis syndromes are characterized by a wide array of manifestations resulting from activation of molecular pathways which control growth, proliferation, and differentiation of a broad range of tissues. Familial gastrointestinal stromal tumors (GISTs) are… read more here.
Keywords: lentigines caf; caf lait; gastrointestinal stromal; stromal tumors ... See more keywords
Familial Gastrointestinal Stromal Tumor Associated with Zebra-like Pigmentation
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DOI: 10.3390/biomedicines11061590
Abstract: Purpose: According to clinical studies, gastrointestinal stromal tumors (GISTs) are predominantly sporadic. GISTs associated with familial syndromes are very rare, and most patients exhibit wild-type KIT and platelet-derived growth factor alpha (PDGFRA). To date, GISTs… read more here.
Keywords: kit; stromal tumor; familial gastrointestinal; germline kit ... See more keywords