Barriers and shortcomings in access to cardiovascular management and prevention for familial hypercholesterolemia during the COVID-19 pandemic.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical cardiology"
DOI: 10.1002/clc.24059
Abstract: Familial hypercholesterolemia (FH) is a hereditary condition caused by mutations in the lipid pathway. The goal in managing FH is to reduce circulating low-density lipoprotein cholesterol and, therefore, reduce the risk of developing atherosclerotic cardiovascular… read more here.
Keywords: access cardiovascular; covid pandemic; familial hypercholesterolemia;
Circulating progenitor cells in patients with familial hypercholesterolemia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21601
Abstract: Familial hypercholesterolemia (FH) is a genetic disease with very high levels of circulating low density lipoprotein cholesterol (LDL‐C) levels that leads to accelerated atherosclerosis. Lipoprotein apheresis is an effective treatment option for patients with FH… read more here.
Keywords: progenitor cells; circulating progenitor; apheresis; familial hypercholesterolemia ... See more keywords
A case report of an Egyptian family with familial hypercholesterolemia and an exonic LINE‐1 insertion in LDLR
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2410
Abstract: Familial hypercholesterolemia (MIM: PS143890) is a genetic disorder characterized by an increase in blood cholesterol. LDLR is one of the genes which their defect contributes to the disorder. Affected individuals may carry a heterozygous variant… read more here.
Keywords: case report; hypercholesterolemia; family familial; report egyptian ... See more keywords
Prevalence of Achilles tendon xanthoma and familial hypercholesterolemia in patients with coronary artery disease undergoing percutaneous coronary intervention
Sign Up to like & getrecommendations! Published in 2019 at "Heart and Vessels"
DOI: 10.1007/s00380-019-01400-6
Abstract: Familial hypercholesterolemia (FH) is reportedly associated with the development of coronary artery disease (CAD), especially acute coronary syndrome (ACS). However, the prevalence of FH in patients with stable CAD is still unclear. The aim of… read more here.
Keywords: stable cad; coronary artery; prevalence; achilles tendon ... See more keywords
Familial Hypercholesterolemia Identification Algorithm in Patients with Acute Cardiovascular Events in A Large Hospital Electronic Database in Bulgaria: A Call for Implementation
Sign Up to like & getrecommendations! Published in 2021 at "Advances in Therapy"
DOI: 10.1007/s12325-020-01608-3
Abstract: Familial hypercholesterolemia (FH) is a genetic disorder characterized by a high level of low-density lipoprotein cholesterol (LDL-C) and is an important cause for premature cardiovascular disease. Because of underdiagnoses, an acute event is often the… read more here.
Keywords: cardiology; treatment; acute cardiovascular; familial hypercholesterolemia ... See more keywords
Evinacumab for Homozygous Familial Hypercholesterolemia: The Italian Cohort of the ELIPSE HoFH Study
Sign Up to like & getrecommendations! Published in 2025 at "Advances in Therapy"
DOI: 10.1007/s12325-025-03160-4
Abstract: Homozygous familial hypercholesterolemia (HoFH) is a severe rare genetic disorder characterized by elevated plasma low-density lipoprotein (LDL) cholesterol levels. Here, we report data from the Italian cohort of the Evinacumab Lipid Studies in Patients with… read more here.
Keywords: cholesterol; elipse hofh; ldl cholesterol; italian cohort ... See more keywords
“I don’t think people should die young”: perspectives of parents with children diagnosed with familial hypercholesterolemia
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Community Genetics"
DOI: 10.1007/s12687-024-00725-8
Abstract: Familial Hypercholesterolemia (FH) is an inherited disorder that significantly increases an individual’s risk of developing premature cardiovascular disease (CVD). Early intervention involving lifestyle modification and medication is crucial in preventing CVD. Prior studies have shown… read more here.
Keywords: uls children; diagnosis; familial hypercholesterolemia; people die ... See more keywords
Significance of lipoprotein(a) levels in familial hypercholesterolemia and coronary artery disease.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.03.021
Abstract: BACKGROUND AND AIMS Patients with familial hypercholesterolemia (FH) are often characterized by premature coronary artery disease (CAD) with heterogeneity at onset. The aim of the present study was to investigate the associations of lipoprotein (a)… read more here.
Keywords: familial hypercholesterolemia; definite probable; coronary artery; artery disease ... See more keywords
Greater preclinical atherosclerosis in treated monogenic familial hypercholesterolemia vs. polygenic hypercholesterolemia
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.05.015
Abstract: Background and aims Familial hypercholesterolemia (FH) is a common inherited disorder of low density lipoprotein-cholesterol (LDL-C) metabolism. It is associated with higher risk of premature coronary heart disease. Around 60% of patients with a clinical… read more here.
Keywords: polygenic hypercholesterolemia; hypercholesterolemia; preclinical atherosclerosis; atherosclerosis treated ... See more keywords
High serum triglyceride concentrations in patients with homozygous familial hypercholesterolemia attenuate the efficacy of lipoprotein apheresis by dextran sulfate adsorption.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.01.005
Abstract: BACKGROUND AND AIMS Maximizing the acute reduction of LDL-cholesterol (C) and lipoprotein (a) (Lp(a)) concentrations in patients with homozygous familial hypercholesterolemia (HoFH) is the main goal of lipoprotein apheresis (LA). The objective of this study… read more here.
Keywords: system; familial hypercholesterolemia; reduction ldl; patients homozygous ... See more keywords
Familial hypercholesterolemia in Canada: Initial results from the FH Canada national registry.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.05.040
Abstract: BACKGROUND AND AIMS Familial hypercholesterolemia (FH) is under-diagnosed and under-treated in most of the world, including Canada. National registries play a key role in identifying patients with FH, understanding gaps in care, and advancing the… read more here.
Keywords: hypercholesterolemia canada; canada national; national registry; familial hypercholesterolemia ... See more keywords