Comprehensive Genetic Analysis of 128 Candidate Genes in a Cohort With Idiopathic, Severe, or Familial Osteoporosis
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DOI: 10.1210/jendso/bvaa148
Abstract: Abstract Context The genetic bases of osteoporosis (OP), a disorder with high heritability, are poorly understood at an individual level. Cases of idiopathic or familial OP have long puzzled clinicians as to whether an actionable… read more here.
Keywords: idiopathic severe; severe familial; 128 candidate; familial osteoporosis ... See more keywords
Whole Genome Sequencing Unravels New Genetic Determinants of Early-Onset Familial Osteoporosis and Low BMD in Malta
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DOI: 10.3390/genes13020204
Abstract: Background: Osteoporosis is a skeletal disease with a strong genetic background. The study aimed to identify the genetic determinants of early-onset familial osteoporosis and low bone mineral density (BMD) in a two-generation Maltese family. Methods:… read more here.
Keywords: determinants early; bmd; genetic determinants; familial osteoporosis ... See more keywords