Risk of Pancreatic Cancer in the Long-Term Prospective Follow-Up of Familial Pancreatic Cancer Kindreds.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the National Cancer Institute"
DOI: 10.1093/jnci/djac167
Abstract: BACKGROUND A family history of pancreatic cancer is associated with increased pancreatic cancer risk. However, risk estimates for individuals in kindreds with an aggregation of pancreatic cancer (>1 relative) are imprecise due to small samples… read more here.
Keywords: pancreatic cancer; risk; familial pancreatic; family history ... See more keywords
Surgical management of familial pancreatic cancer: a systematic review of the literature
Sign Up to like & getrecommendations! Published in 2022 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.17834
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is the third most common cause of cancer‐related mortality. The fact that the vast majority of patients with PDAC are diagnosed at an advanced stage highlights the need of early diagnosis.… read more here.
Keywords: pancreatic cancer; management familial; familial pancreatic; cancer systematic ... See more keywords
Genomic analysis of familial pancreatic cancers and intraductal papillary mucinous neoplasms: A cross‐sectional study
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DOI: 10.1111/cas.15316
Abstract: Environmental and genetic factors play a critical role in the pathogenesis of pancreatic cancer, which is likely to follow a multistep process that includes intraductal papillary mucinous neoplasm. The pathogenesis of familial pancreatic cancer has… read more here.
Keywords: mucinous neoplasm; pancreatic cancer; familial pancreatic; papillary mucinous ... See more keywords
Somatic Mutation Profiling in the Liquid Biopsy and Clinical Analysis of Hereditary and Familial Pancreatic Cancer Cases Reveals KRAS Negativity and a Longer Overall Survival
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DOI: 10.3390/cancers13071612
Abstract: Simple Summary Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis. KRAS mutations occur in up to 95% of cases and render the tumor resistant to many types of therapy. Therefore, these patients are treated with… read more here.
Keywords: familial pancreatic; pancreatic cancer; hereditary familial; overall survival ... See more keywords
Molecular Features and Clinical Management of Hereditary Pancreatic Cancer Syndromes and Familial Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031205
Abstract: Hereditary pancreatic cancers are caused by several inherited genes. Familial pancreatic cancer is defined as pancreatic cancer arising in a patient with at least two first-degree relatives with pancreatic cancer in the absence of an… read more here.
Keywords: cancer; cancer syndromes; hereditary pancreatic; familial pancreatic ... See more keywords
Hereditary vs Familial Pancreatic Cancer: Associated Genetic Syndromes and Clinical Perspective.
Sign Up to like & getrecommendations! Published in 2020 at "Oncology"
DOI: 10.46883/onc.3406.0196
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a disease marked by high rates of mortality; it is mostly incurable at the time of diagnosis. Only about 7% of patients survive 5 years after diagnosis. Diagnosis at a… read more here.
Keywords: familial pancreatic; pancreatic cancer; hereditary familial; cancer ... See more keywords
Familial Pancreatic Cancer and the Future of Directed Screening
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DOI: 10.5009/gnl16414
Abstract: Pancreatic cancer (PC) is the third most common cause of cancer-related death in the United States and the 12th most common worldwide. Mortality is high, largely due to late stage of presentation and suboptimal treatment… read more here.
Keywords: familial pancreatic; directed screening; future directed; pancreatic cancer ... See more keywords