IL-1 Family Cytokine Pathways Underlying NAFLD: Towards New Treatment Strategies.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2018.03.005
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. Pathways responsible for the activation of IL-1 family cytokines are key in the development of NAFLD but underlying mechanisms are not fully understood.… read more here.
Keywords: underlying nafld; family cytokine; family; nafld towards ... See more keywords
Structural insights into the assembly of gp130 family cytokine signaling complexes
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DOI: 10.1101/2022.06.30.496838
Abstract: The gp130 family cytokine signaling complexes have limited structural information despite their crucial roles in various cellular processes. We determined cryo-EM structures of several complexes of this family, containing full ectodomains of both signaling receptors… read more here.
Keywords: family; gp130 family; structural insights; cytokine signaling ... See more keywords
IL-1 Family Cytokine Regulation of Vascular Permeability and Angiogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01426
Abstract: The IL-1 family of cytokines are well-known for their primary role in initiating inflammatory responses both in response to and acting as danger signals. It has long been established that IL-1 is capable of simultaneously… read more here.
Keywords: angiogenesis; family cytokine; family; cytokine regulation ... See more keywords