Interleukin-10 Family Cytokines Immunobiology and Structure.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-9367-9_4
Abstract: The Interleukin (IL)-10 cytokine family includes IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26, which are considered as Class 2α-helical cytokines. IL-10 is the most important cytokine in suppressing pro-inflammatory responses in all kinds of autoimmune… read more here.
Keywords: interleukin family; immunobiology structure; family; cytokines immunobiology ... See more keywords
Structural Insights into the Interleukin-17 Family Cytokines and Their Receptors.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-9367-9_5
Abstract: The IL-17 family in humans consists of six distinct cytokines (IL-17A-F) that can interact with five IL-17 receptors (IL-17RA-E). The interaction between these cytokines and their receptors are critical in mediating host defenses while also… read more here.
Keywords: cytokines receptors; interleukin family; structural insights; family ... See more keywords
The IL-1 family of cytokines. Do they have a role in scleroderma fibrosis?
Sign Up to like & getrecommendations! Published in 2018 at "Immunology letters"
DOI: 10.1016/j.imlet.2017.11.012
Abstract: Systemic sclerosis is a profibrotic autoimmune disease mediated by the dysregulation in collagen synthesis, leading to the increased deposition of collagens, primarily type I and III, and the deposition of other extracellular matrix proteins in… read more here.
Keywords: family cytokines; cytokines role; fibrosis; pathology ... See more keywords
New perspectives on IL-33 and IL-1 family cytokines as innate environmental sensors.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Society transactions"
DOI: 10.1042/bst20170567
Abstract: Interleukin (IL)-1 family cytokines are important initiators of innate immunity and host defence; however, their uncontrolled activities can cause tissue-damaging inflammation. Consequently, IL-1 family cytokines have sophisticated regulatory mechanisms to control their activities including proteolytic… read more here.
Keywords: new perspectives; family; perspectives family; family cytokines ... See more keywords
Interleukin‐17 family cytokines in protective immunity against infections: role of hematopoietic cell‐derived and non‐hematopoietic cell‐derived interleukin‐17s
Sign Up to like & getrecommendations! Published in 2018 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12560
Abstract: Interleukin‐17 family cytokines, consisting of six members, participate in immune response in infections and autoimmune and inflammatory diseases. The prototype cytokine of the family, IL‐17A, was originally identified from CD4+ T cells which are now… read more here.
Keywords: interleukin family; cell derived; family; hematopoietic cell ... See more keywords
Therapeutic potential of targeting interleukin‐1 family cytokines in chronic inflammatory skin diseases *
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Dermatology"
DOI: 10.1111/bjd.20975
Abstract: The interleukin (IL)‐1 family of cytokines is a central regulator of a myriad of immunological responses. It comprises several cytokines, including those belonging to the IL‐1, IL‐36 and IL‐18 subfamilies, as well as IL‐33. The… read more here.
Keywords: skin; family; family cytokines; inflammatory skin ... See more keywords
STAT3 signaling induced by IL-6 family cytokines modulates angiogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell science"
DOI: 10.1242/jcs.260182
Abstract: Aberrant angiogenesis is a hallmark of cardiovascular and retinal neovascular disease. The STAT3 pathway represents a potential pharmacological target for those diseases due to its impact on angiogenesis. Surprisingly some STAT3 activators including the IL6… read more here.
Keywords: stat3 signaling; cytokines modulates; stat3; induced family ... See more keywords
The Roles of IL-1 Family Cytokines in the Pathogenesis of Systemic Sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02025
Abstract: The IL-1 family consists of 11 cytokines, 7 ligands with agonist activity (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and four members with antagonistic activities [IL-1 receptor antagonist (IL-1Ra), IL-36Ra, IL-37, IL-38]. Recent articles have… read more here.
Keywords: cytokines pathogenesis; roles family; family; systemic sclerosis ... See more keywords
IL-1α and IL-36 Family Cytokines Can Undergo Processing and Activation by Diverse Allergen-Associated Proteases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.879029
Abstract: Inflammation driven by environmental allergens is an important source of morbidity in diseases such as asthma and eczema. How common allergens promote inflammation is still poorly understood, but previous studies have implicated the protease activity… read more here.
Keywords: undergo processing; family; processing activation; activity ... See more keywords
IL-10 family cytokines in chronic rhinosinusitis with nasal polyps: From experiments to the clinic
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.947983
Abstract: Chronic rhinosinusitis with nasal polyps (CRSwNP) is considered a nasal sinus inflammatory disease that can be dominated by immune cells and cytokines. IL-10 family cytokines exert essential functions in immune responses during infection and inflammation.… read more here.
Keywords: family; nasal polyps; rhinosinusitis nasal; chronic rhinosinusitis ... See more keywords
Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13091643
Abstract: Interleukin-17 (IL-17) family cytokines are potent drivers of inflammatory responses. Although IL-17 was originally identified as a cytokine that induces protective effects against bacterial and fungal infections, IL-17 can also promote chronic inflammation in a… read more here.
Keywords: cytokines metabolic; metabolic disorders; interleukin family; cancer ... See more keywords