Leveraging family data to design Mendelian Randomization that is provably robust to population stratification.
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DOI: 10.1101/gr.277664.123
Abstract: Mendelian Randomization (MR) has emerged as a powerful approach to leverage genetic instruments to infer causality between pairs of traits in observational studies. However, the results of such studies are susceptible to biases due to… read more here.
Keywords: provably robust; mendelian randomization; family data; population ... See more keywords