A novel presenilin 1 mutation (F388L) identified in a Chinese family with early-onset Alzheimer's disease
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DOI: 10.1016/j.neurobiolaging.2016.10.010
Abstract: A subset of Alzheimer's disease (AD) occurrence shows autosomal dominant, familial inheritance patterns. Such familial AD (FAD) are caused by mutations in APP, PSEN1, and PSEN2 genes, which encode amyloid-β (Aβ) precursor protein, presenilin 1… read more here.
Keywords: family early; mutation; chinese family; alzheimer disease ... See more keywords